The concept of molecular mimicry was established to explain commonalities of structure
which developed in response to evolutionary pressures. Most examples of molecular …

Although great advances in elucidating the molecular basis and pathogenesis of
Alzheimer's disease (AD) have been made and multifarious novel therapeutic approaches …

Protein misfolding is intimately associated with devastating human neurodegenerative
diseases, including Alzheimer's, Huntington's, and Parkinson's. Although disparate in their …

In ageing populations, neurodegenerative diseases increase in prevalence, exacting an
enormous toll on individuals and their communities. Multiple complementary experimental …

Amyloid diseases are a group of degenerative disorders characterized by cell/tissue
damage caused by toxic protein aggregates. Abnormal production, processing and/or …

Abstract Amyloid beta 42 (Abeta42) is the principal trigger of neurodegeneration during
Alzheimer's disease (AD). However, the etiology of its noxious cellular effects remains …

The lack of effective therapies that slow the progression of Alzheimer's disease (AD) and
related tauopathies highlights the need for a more comprehensive understanding of the …

The rise of neurodegenerative diseases in an aging population is an increasing problem of
health, social and economic consequences. Epidemiological and intervention studies have …

Several neurodegenerative diseases, such as Parkinson's disease (PD), Alzheimer's
disease (AD), Huntington's disease (HD), amyotrophic lateral sclerosis (ALS), or prion …

Protein misfolding and aggregation are central events in many disorders including several
neurodegenerative diseases. This suggests that alterations in normal protein homeostasis …