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d-Amino acids: new clinical pathways for brain diseases
Free d-amino acids (d-AAs) are emerging as a novel and important class of signaling
molecules in many organs, including the brain and endocrine systems. There has been …
molecules in many organs, including the brain and endocrine systems. There has been …
d‐Amino acids in biological systems
S Du, M Wey, DW Armstrong - Chirality, 2023 - Wiley Online Library
Investigations on the occurrence and biochemical roles of free D‐amino acids and D‐amino
acid‐containing peptides and proteins in living systems have increased in frequency and …
acid‐containing peptides and proteins in living systems have increased in frequency and …
Bisphenol F induces liver-gut alteration in zebrafish
H Wang, S Qi, X Mu, L Yuan, Y Li, J Qiu - Science of The Total Environment, 2022 - Elsevier
The unease of consumers with bisphenol A has led to the increased industrial usage of
bisphenol F (BPF), which is a new hazard to environmental health. Here, zebrafish were …
bisphenol F (BPF), which is a new hazard to environmental health. Here, zebrafish were …
L‐serine: a neglected amino acid with a potential therapeutic role in diabetes
L‐serine is classified as a non‐essential amino acid; however, L‐serine is indispensable
having a central role in a broad range of cellular processes. Growing evidence suggests a …
having a central role in a broad range of cellular processes. Growing evidence suggests a …
d-Alanine: Distribution, origin, physiological relevance, and implications in disease
Abstract d-Alanine (d-Ala) is an unusual endogenous amino acid present in invertebrates
and vertebrates. Compared to its l-isomer, the characterization of d-Ala is challenging …
and vertebrates. Compared to its l-isomer, the characterization of d-Ala is challenging …
New therapeutic targets and drugs for schizophrenia beyond dopamine D2 receptor antagonists
A Peng, J Chai, H Wu, B Bai, H Yang… - Neuropsychiatric …, 2024 - Taylor & Francis
Schizophrenia is a disease with a complex pathological mechanism that is influenced by
multiple genes. The study of its pathogenesis is dominated by the dopamine hypothesis, as …
multiple genes. The study of its pathogenesis is dominated by the dopamine hypothesis, as …
d-Amino acids in mammalian endocrine tissues
G Chieffi Baccari, S Falvo, A Santillo… - Amino Acids, 2020 - Springer
Abstract d-Aspartate, d-serine and d-alanine are a regular occurrence in mammalian
endocrine tissues, though in amounts varying with the type of gland. The pituitary gland …
endocrine tissues, though in amounts varying with the type of gland. The pituitary gland …
Asc-1 regulates white versus beige adipocyte fate in a subcutaneous stromal cell population
L Suwandhi, I Altun, R Karlina, V Miok… - Nature …, 2021 - nature.com
Adipose tissue expansion, as seen in obesity, is often metabolically detrimental causing
insulin resistance and the metabolic syndrome. However, white adipose tissue expansion at …
insulin resistance and the metabolic syndrome. However, white adipose tissue expansion at …
The neutral amino acid transporter SLC7A10 in adipose tissue, obesity and insulin resistance
RÅ Jersin, LR Jonassen, SN Dankel - Frontiers in cell and …, 2022 - frontiersin.org
Obesity, insulin resistance and type 2 diabetes represent major global health challenges,
and a better mechanistic understanding of the altered metabolism in these conditions may …
and a better mechanistic understanding of the altered metabolism in these conditions may …
[HTML][HTML] Dysfunction of the NMDA Receptor in the Pathophysiology of Schizophrenia and/or the Pathomechanisms of Treatment-Resistant Schizophrenia
R Okubo, M Okada, E Motomura - Biomolecules, 2024 - mdpi.com
For several decades, the dopamine hypothesis contributed to the discovery of numerous
typical and atypical antipsychotics and was the sole hypothesis for the pathophysiology of …
typical and atypical antipsychotics and was the sole hypothesis for the pathophysiology of …