Current challenges and future directions for engineering extracellular vesicles for heart, lung, blood and sleep diseases
Extracellular vesicles (EVs) carry diverse bioactive components including nucleic acids,
proteins, lipids and metabolites that play versatile roles in intercellular and interorgan …
proteins, lipids and metabolites that play versatile roles in intercellular and interorgan …
Harmonising cellular conversations: decoding the vital roles of extracellular vesicles in respiratory system intercellular communications
Extracellular vesicles (EVs) released by various cells play crucial roles in intercellular
communication within the respiratory system. This review explores the historical context and …
communication within the respiratory system. This review explores the historical context and …
MicroRNA-212-5p, an anti-proliferative miRNA, attenuates hypoxia and sugen/hypoxia-induced pulmonary hypertension in rodents
T Chen, MR Sun, Q Zhou, AM Guzman… - … Therapy-Nucleic Acids, 2022 - cell.com
MicroRNAs (miRNA, miR-) play important roles in disease development. In this study, we
identified an anti-proliferative miRNA, miR-212-5p, that is induced in pulmonary artery …
identified an anti-proliferative miRNA, miR-212-5p, that is induced in pulmonary artery …
[HTML][HTML] Insight into endothelial cell-derived extracellular vesicles in cardiovascular disease: molecular mechanisms and clinical implications
X Wang, B He - Pharmacological Research, 2024 - Elsevier
The endothelium is crucial in regulating vascular function. Extracellular vesicles (EVs) serve
as membranous structures released by cells to facilitate intercellular communication through …
as membranous structures released by cells to facilitate intercellular communication through …
A Machine Learning Model Based on microRNAs for the Diagnosis of Essential Hypertension
A Jusic, I Junuzovic, A Hujdurovic, L Zhang, M Vausort… - Non-coding RNA, 2023 - mdpi.com
Introduction: Hypertension is a major and modifiable risk factor for cardiovascular diseases.
Essential, primary, or idiopathic hypertension accounts for 90–95% of all cases. Identifying …
Essential, primary, or idiopathic hypertension accounts for 90–95% of all cases. Identifying …
Extracellular vesicles in pulmonary hypertension: a dangerous liaison?
M Conti, M Minniti, M Tiné, M De Francesco, R Gaeta… - Biology, 2023 - mdpi.com
Simple Summary This review discusses the role of extracellular vesicles in pulmonary
hypertension a serious and progressive lung disease characterized by high blood pressure …
hypertension a serious and progressive lung disease characterized by high blood pressure …
Emerging role of exosomes in vascular diseases
Y Ren, H Zhang - Frontiers in Cardiovascular Medicine, 2023 - frontiersin.org
Exosomes are biological small spherical lipid bilayer vesicles secreted by most cells in the
body. Their contents include nucleic acids, proteins, and lipids. Exosomes can transfer …
body. Their contents include nucleic acids, proteins, and lipids. Exosomes can transfer …
Extracellular vesicles in venous thromboembolism and pulmonary hypertension
J Zhang, X Hu, T Wang, R **ao, L Zhu, M Ruiz… - Journal of …, 2023 - Springer
Venous thromboembolism (VTE) is a multifactorial disease, and pulmonary hypertension
(PH) is a serious condition characterized by pulmonary vascular remodeling leading with …
(PH) is a serious condition characterized by pulmonary vascular remodeling leading with …
Tadalafil Enhances the Therapeutic Efficacy of Mesenchymal Stem Cells-Derived Exosomes in Pulmonary Hypertension by Upregulating miR-29a-3p
Y Liu, C He, Q Zhong, X Shi, H Li, G Fu… - International Journal …, 2024 - Taylor & Francis
Introduction Pulmonary hypertension (PH) is a progressive and life-threatening condition.
Recent research has demonstrated that exosomes derived from mesenchymal stem cells …
Recent research has demonstrated that exosomes derived from mesenchymal stem cells …
Roles and Potential Mechanisms of Endothelial Cell-Derived Extracellular Vesicles in Ischemic Stroke
X Yu, Y Huang, C Li - Translational Stroke Research, 2025 - Springer
The etiology and mechanisms of ischemic stroke are complex, encompassing a variety of
pathological processes including atherosclerosis, energy failure, neuroinflammation, blood …
pathological processes including atherosclerosis, energy failure, neuroinflammation, blood …