Pulmonary vascular changes in asthma and COPD

LM Harkness, V Kanabar, HS Sharma… - Pulmonary …, 2014 - Elsevier
In chronic lung disorders such as in asthma and chronic obstructive pulmonary disease
(COPD) there is increased bronchial angiogenesis and remodelling of pulmonary vessels …

[HTML][HTML] Circulating endothelial and progenitor cells: Evidence from acute and long-term exercise effects

M Koutroumpi, S Dimopoulos, K Psarra… - World Journal of …, 2012 - ncbi.nlm.nih.gov
Circulating bone-marrow-derived cells, named endothelial progenitor cells (EPCs), are
capable of maintaining, generating, and replacing terminally differentiated cells within their …

Dysfunction of endothelial progenitor cells from smokers and chronic obstructive pulmonary disease patients due to increased DNA damage and senescence

KE Paschalaki, RD Starke, Y Hu, N Mercado… - Stem …, 2013 - academic.oup.com
Cardiovascular disease (CVD) is a major cause of death in smokers, particularly in those
with chronic obstructive pulmonary disease (COPD). Circulating endothelial progenitor cells …

Mechanisms of acute exacerbation of respiratory symptoms in chronic obstructive pulmonary disease

M Roca, A Verduri, L Corbetta, E Clini… - European journal of …, 2013 - Wiley Online Library
Exacerbations of chronic obstructive respiratory disease (ECOPD) are acute events
characterized by worsening of the patient's respiratory symptoms, particularly dyspnoea …

Cigarette smoke extract mediates cell premature senescence in chronic obstructive pulmonary disease patients by up-regulating USP7 to activate p300-p53/p21 …

M Zeng, X Zhang, W **ng, Q Wang, G Liang, Z He - Toxicology Letters, 2022 - Elsevier
Objectives Tobacco hazard is one of the most severe public health issues in the world. It is
believed that smoking is the most important factor leading to chronic obstructive pulmonary …

Circulating progenitor cells and vascular dysfunction in chronic obstructive pulmonary disease

S Pizarro, J García-Lucio, VI Peinado, O Tura-Ceide… - PloS one, 2014 - journals.plos.org
Background In chronic obstructive pulmonary disease (COPD), decreased progenitor cells
and impairment of systemic vascular function have been suggested to confer higher …

Endothelial progenitor cells as therapeutic agents in the microcirculation: an update

C Napoli, T Hayashi, F Cacciatore, A Casamassimi… - Atherosclerosis, 2011 - Elsevier
This review evaluates novel beneficial effects of circulating endothelial progenitor cells
(EPCs) as shown by several preclinical studies and clinical trials carried out to test the safety …

Pro-angiogenic hematopoietic progenitor cells and endothelial colony-forming cells in pathological angiogenesis of bronchial and pulmonary circulation

HT Duong, SC Erzurum, K Asosingh - Angiogenesis, 2011 - Springer
Dysregulation of angiogenesis is a common feature of many disease processes. Vascular
remodeling is believed to depend on the participation of endothelial progenitor cells, but the …

Vasculogenic stem and progenitor cells in human: future cell therapy product or liquid biopsy for vascular disease

DM Smadja - Stem Cells: Therapeutic Applications, 2019 - Springer
New blood vessel formation in adults was considered to result exclusively from sprouting of
preexisting endothelial cells, a process referred to angiogenesis. Vasculogenesis, the …

Endothelial progenitor cells in chronic obstructive pulmonary disease and emphysema

MF Doyle, RP Tracy, MA Parikh, EA Hoffman… - PLoS …, 2017 - journals.plos.org
Endothelial injury is implicated in the pathogenesis of COPD and emphysema; however the
role of endothelial progenitor cells (EPCs), a marker of endothelial cell repair, and …