Medical gas therapy for tissue, organ, and CNS protection: a systematic review of effects, mechanisms, and challenges

RD Zafonte, L Wang, CA Arbelaez… - Advanced …, 2022‏ - Wiley Online Library
Gaseous molecules have been increasingly explored for therapeutic development. Here,
following an analytical background introduction, a systematic review of medical gas …

Lung MRI with hyperpolarised gases: current & future clinical perspectives

NJ Stewart, LJ Smith, HF Chan… - The British Journal of …, 2022‏ - academic.oup.com
The use of pulmonary MRI in a clinical setting has historically been limited. Whilst CT
remains the gold-standard for structural lung imaging in many clinical indications, technical …

[HTML][HTML] CT mucus score and 129Xe MRI ventilation defects after 2.5 years' anti-IL-5Rα in eosinophilic asthma

MJ McIntosh, HK Kooner, RL Eddy, A Wilson… - Chest, 2023‏ - Elsevier
Background We previously showed in patients with poorly controlled eosinophilic asthma
that a single dose of benralizumab resulted in significantly improved Asthma Control …

Mucus Plugs in Asthma at CT Associated with Regional Ventilation Defects at 3He MRI

DG Mummy, EM Dunican, KJ Carey, MD Evans… - Radiology, 2022‏ - pubs.rsna.org
Background Airway mucus plugs in asthma are associated with exacerbation frequency,
increased eosinophilia, and reduced lung function. The relationship between mucus plugs …

Structure and function of small airways in asthma patients revisited

WB van den Bosch, AL James… - European Respiratory …, 2021‏ - publications.ersnet.org
Small airways (< 2 mm in diameter) are probably involved across almost all asthma
severities and they show proportionally more structural and functional abnormalities with …

Heterogeneity of airway smooth muscle remodeling in asthma

AL James, GM Donovan, FHY Green… - American journal of …, 2023‏ - atsjournals.org
Rationale: Ventilatory defects in asthma are heterogeneous and may represent the
distribution of airway smooth muscle (ASM) remodeling. Objectives: To determine the …

Is computed tomography airway count related to asthma severity and airway structure and function?

RL Eddy, S Svenningsen, M Kirby… - American Journal of …, 2020‏ - atsjournals.org
Rationale: In patients with asthma, X-ray computed tomography (CT) has provided evidence
of thickened airway walls and airway occlusions, but the total number of CT-visible airways …

Functional lung imaging using novel and emerging MRI techniques

CT Foo, D Langton, BR Thompson, F Thien - Frontiers in Medicine, 2023‏ - frontiersin.org
Respiratory diseases are leading causes of death and disability in the world. While early
diagnosis is key, this has proven difficult due to the lack of sensitive and non-invasive tools …

Quantification of pulmonary functional MRI: state-of-the-art and emerging image processing methods and measurements

M Sharma, PV Wyszkiewicz… - Physics in Medicine …, 2022‏ - iopscience.iop.org
Pulmonary functional magnetic resonance imaging (PfMRI) provides a way to non-invasively
map and measure the spatial distribution of pulmonary ventilation, perfusion and gas …

Lung magnetic resonance imaging: technical advancements and clinical applications

Y Ohno, Y Ozawa, H Nagata, T Ueda… - Investigative …, 2024‏ - journals.lww.com
Since lung magnetic resonance imaging (MRI) became clinically available, limited clinical
utility has been suggested for applying MRI to lung diseases. Moreover, clinical applications …