With the development of nanotechnology, nanocarriers have been increasingly used for
curative drug/gene delivery. Various nanocarriers are being introduced and assessed, such …

The rising global incidence of acute and chronic kidney diseases has increased the demand
for renal replacement therapy. This issue, compounded with the limited availability of viable …

Multidrug resistance remains one of the main obstacles to efficient chemotherapy of
colorectal cancer. Herein, an efficient combination therapeutic strategy is proposed based …

Ultrasound is not only the most widely used medical imaging mode for diagnostics owing to
its real-time, non-radiation, portable and low-cost merits, but also a promising targeted …

Ultrasound has been studied as a promising tool for intracellular gene delivery. In this work,
we studied gene transfection of a human prostate cancer cell line exposed to megahertz …

Mesenchymal stem cells (MSCs) hold tremendous potential as a targeted cell-based
delivery platform for inflammatory and cancer therapy. Genetic manipulation of MSCs …

Ultrasound‑targeted microbubble destruction (UTMD) can promote the entry of plasmid DNA
(pDNA) into the cell cytoplasm, by increasing the permeability of the cell membrane. But the …

The microbubble is a kind of clinically applied ultrasound contrast agent in disease
diagnosis that can also rupture under sonication to increase membrane permeability and …

Methacryloyloxy ethyl trimethyl ammonium chloride (TMA) is a potent polymeric plasma DNA
(pDNA) carrier. The present study shows that TMA/pDNA polyplexes could be internalized …

Objetivos: El objetivo de este estudio fue realizar una revisión sistemática sobre los
diferentes efectos y parámetros dosimétricos de la irradiación ultrasónica terapéutica en el …