The prevalence of both Alzheimer's disease (AD) and vascular dementia (VaD) is increasing
with the aging of the population. Studies from the last several years have shown that people …

Metformin, a widely prescribed medication for type 2 diabetes, has garnered increasing
attention for its potential neuroprotective properties due to the growing demand for …

Sporadic Alzheimer's disease (sAD) is the most common form of dementia. Rats injected
intracerebroventricularly with streptozotocin (STZ-icv) develop insulin-resistant brain state …

Aims The relationship between type 2 diabetes and Alzheimer's disease (AD) provides
evidence that insulin and insulin sensitizers may be beneficial for the treatment of AD. The …

Alzheimer's disease (AD) is the most common neurodegenerative disorder with the majority
of patients classified as sporadic AD (sAD), in which etiopathogenesis remains unresolved …

Alzheimer's disease (AD) is associated with reduced insulin level and impairment of insulin
receptor (IR) signaling in the brain, which correlates to amyloid pathology …

The intracerebroventricularly (icv) injected streptozotocin (STZ) induced brain state is a
widely used model of sporadic Alzheimer-disease (AD). However, data have been …

Alzheimer's disease (AD) is characterized by multiple cognitive deficits including memory
and sensorimotor gating impairments as a result of neuronal and synaptic loss. The …

Alzheimer's disease (AD) is the most common neurodegenerative disorder among the
elderly. In the light of increasing AD prevalence and lack of effective treatment, new …

Paeoniflorin (PF) is a natural monoterpene glycoside in Paeonia lactiflora pall with anti-
diabetic, antioxidant, anti-inflammatory, and neuro-protective properties. This study was …