ERS statement on respiratory muscle testing at rest and during exercise

P Laveneziana, A Albuquerque… - European …, 2019 - publications.ersnet.org
Assessing respiratory mechanics and muscle function is critical for both clinical practice and
research purposes. Several methodological developments over the past two decades have …

Dyspnea in COPD: new mechanistic insights and management implications

DE O'Donnell, KM Milne, MD James, JP de Torres… - Advances in …, 2020 - Springer
Dyspnea is the most common symptom experienced by patients with chronic obstructive
pulmonary disease (COPD). To avoid exertional dyspnea, many patients adopt a sedentary …

Effects of inspiratory muscle training in COPD patients: A systematic review and meta‐analysis

M Beaumont, P Forget, F Couturaud… - The clinical respiratory …, 2018 - Wiley Online Library
Objectives In chronic obstructive pulmonary disease (COPD), quality of life and exercise
capacity are altered in relationship to dyspnea. Benefits of inspiratory muscle training (IMT) …

Inspiratory muscle training reduces diaphragm activation and dyspnea during exercise in COPD

D Langer, C Ciavaglia, A Faisal… - Journal of applied …, 2018 - journals.physiology.org
Among patients with chronic obstructive pulmonary disease (COPD), those with the lowest
maximal inspiratory pressures experience greater breathing discomfort (dyspnea) during …

Pulmonary gas exchange abnormalities in mild chronic obstructive pulmonary disease. Implications for dyspnea and exercise intolerance

AF Elbehairy, CE Ciavaglia, KA Webb… - American journal of …, 2015 - atsjournals.org
Rationale: Several studies in mild chronic obstructive pulmonary disease (COPD) have
shown a higher than normal ventilatory equivalent for carbon dioxide (V. e/V. co2) during …

Common mechanisms of dyspnea in chronic interstitial and obstructive lung disorders

A Faisal, BJ Alghamdi, CE Ciavaglia… - American journal of …, 2016 - atsjournals.org
Rationale: The mechanisms underlying dyspnea in interstitial lung disease (ILD) and
chronic obstructive pulmonary disease (COPD) are unknown. Objectives: To examine …

Activity-related dyspnea in chronic obstructive pulmonary disease: physical and psychological consequences, unmet needs, and future directions

NA Hanania, DE O'Donnell - International journal of chronic …, 2019 - Taylor & Francis
Dyspnea is a distressing, debilitating, and near-ubiquitous symptom affecting patients with
COPD. In addition to the functional consequences of dyspnea, which include activity …

Muscle dysfunction in chronic obstructive pulmonary disease: update on causes and biological findings

J Gea, S Pascual, C Casadevall… - Journal of thoracic …, 2015 - pmc.ncbi.nlm.nih.gov
Respiratory and/or limb muscle dysfunction, which are frequently observed in chronic
obstructive pulmonary disease (COPD) patients, contribute to their disease prognosis …

Sex differences in large conducting airway anatomy

PB Dominelli, JG Ripoll, TJ Cross… - Journal of applied …, 2018 - journals.physiology.org
Airway luminal area is the major determinant of resistance to airflow in the tracheobronchial
tree. Women may have smaller central conducting airways than men; however, previous …

Sex-differences in COPD: from biological mechanisms to therapeutic considerations

KM Milne, RA Mitchell, ON Ferguson, AS Hind… - Frontiers in …, 2024 - frontiersin.org
Chronic obstructive pulmonary disease (COPD) is a heterogeneous respiratory condition
characterized by symptoms of dyspnea, cough, and sputum production. We review sex …