[HTML][HTML] Next-generation feedstocks methanol and ethylene glycol and their potential in industrial biotechnology

N Wagner, L Wen, CJR Frazão, T Walther - Biotechnology Advances, 2023 - Elsevier
Microbial fermentation processes are expected to play an important role in reducing
dependence on fossil-based raw materials for the production of everyday chemicals. In …

[HTML][HTML] Methanol-based biomanufacturing of fuels and chemicals using native and synthetic methylotrophs

A Sarwar, EY Lee - Synthetic and Systems Biotechnology, 2023 - Elsevier
Methanol has recently gained significant attention as a potential carbon substrate for the
production of fuels and chemicals, owing to its high degree of reduction, abundance, and …

Reprogramming methanol utilization pathways to convert Saccharomyces cerevisiae to a synthetic methylotroph

C Zhan, X Li, G Lan, EEK Baidoo, Y Yang, Y Liu… - Nature Catalysis, 2023 - nature.com
Methanol, an organic one-carbon (C1) compound, represents an attractive alternative
carbon source for microbial fermentation. Despite considerable advancements in methanol …

In vivo implementation of a synthetic metabolic pathway for the carbon-conserving conversion of glycolaldehyde to acetyl-CoA

N Wagner, F Bade, E Straube, K Rabe… - … in Bioengineering and …, 2023 - frontiersin.org
Ethylene glycol (EG) derived from plastic waste or CO2 can serve as a substrate for
microbial production of value-added chemicals. Assimilation of EG proceeds though the …

Current trends and possibilities of typical microbial protein production approaches: a review

JT He, M Tang, FF Zhong, J Deng, W Li… - Critical Reviews in …, 2024 - Taylor & Francis
Global population growth and demographic restructuring are driving the food and agriculture
sectors to provide greater quantities and varieties of food, of which protein resources are …

Engineering yeast for high-level production of β-farnesene from sole methanol

J Li, J Gao, M Ye, P Cai, W Yu, X Zhai, YJ Zhou - Metabolic Engineering, 2024 - Elsevier
Methanol, a rich one-carbon feedstock, can be massively produced from CO 2 by the liquid
sunshine route, which is helpful to realize carbon neutrality. β-Farnesene is widely used in …

[HTML][HTML] Harnessing noncanonical redox cofactors to advance synthetic assimilation of one-carbon feedstocks

E Orsi, JM Hernández-Sancho, MS Remeijer… - Current Opinion in …, 2024 - Elsevier
Highlights•We discuss the use of NCRCs for supporting one-carbon assimilation.•
Engineered one-carbon oxidizing enzymes can accept NCRCs.•NCRCs can lower the …

[HTML][HTML] Perspectives for Using CO2 as a Feedstock for Biomanufacturing of Fuels and Chemicals

E Kurt, J Qin, A Williams, Y Zhao, D **e - Bioengineering, 2023 - mdpi.com
Microbial cell factories offer an eco-friendly alternative for transforming raw materials into
commercially valuable products because of their reduced carbon impact compared to …

Microbial conversion of ethanol to high-value products: progress and challenges

M Sun, AX Gao, X Liu, Z Bai, P Wang… - … for Biofuels and …, 2024 - Springer
Industrial biotechnology heavily relies on the microbial conversion of carbohydrate
substrates derived from sugar-or starch-rich crops. This dependency poses significant …

[HTML][HTML] Industrializing methanotrophs and other methylotrophic bacteria: from bioengineering to product recovery

D Sauvageau, LY Stein, E Arenas, S Das… - Current Opinion in …, 2024 - Elsevier
Microbes that use the single-carbon substrates methanol and methane offer great promise to
bioindustry along with substantial environmental benefits. Methanotrophs and other …