Bioactives of Momordica charantia as Potential Anti-Diabetic/Hypoglycemic Agents
Momordica charantia L., a member of the Curcubitaceae family, has traditionally been used
as herbal medicine and as a vegetable. Functional ingredients of M. charantia play …
as herbal medicine and as a vegetable. Functional ingredients of M. charantia play …
JAK/STAT signaling in diabetic kidney disease
Y Liu, W Wang, J Zhang, S Gao, T Xu… - Frontiers in Cell and …, 2023 - frontiersin.org
Diabetic kidney disease (DKD) is the most important microvascular complication of diabetes
and the leading cause of end-stage renal disease (ESRD) worldwide. The Janus …
and the leading cause of end-stage renal disease (ESRD) worldwide. The Janus …
Nanomedicines for the management of diabetic nephropathy: present progress and prospects
Diabetic nephropathy (DN) is a serious microvascular consequence of diabetes mellitus
(DM), posing an encumbrance to public health worldwide. Control over the onset and …
(DM), posing an encumbrance to public health worldwide. Control over the onset and …
Role of Fenugreek, Cinnamon, Curcuma longa, Berberine and Momordica charantia in Type 2 Diabetes Mellitus Treatment: A Review
M Cortez-Navarrete, KG Pérez-Rubio… - Pharmaceuticals, 2023 - mdpi.com
Type 2 diabetes mellitus (T2DM) is a complex disease that has become a major global
health concern. Given the efficacy of antidiabetic drugs, pharmacological therapy is …
health concern. Given the efficacy of antidiabetic drugs, pharmacological therapy is …
Suppression of sonic hedgehog pathway-based proliferation in glioblastoma cells by small-size silver nanoparticles in vitro
B Skóra, M Masicz, P Nowak, J Lachowska… - Archives of …, 2023 - Springer
Glioblastomas (GBs) are one of the most aggressive and invasive intracranial cancers.
Recently, it has been postulated that, among other factors, the hedgehog (HH) pathway may …
Recently, it has been postulated that, among other factors, the hedgehog (HH) pathway may …
Gene expression profiling and protein analysis reveal suppression of the C-Myc oncogene and inhibition JAK/STAT and PI3K/AKT/mTOR signaling by thymoquinone …
Overexpression of c-Myc plays an essential role in leukemogenesis and drug resistance,
making c-Myc an attractive target for cancer therapy. However, targeting c-Myc directly is …
making c-Myc an attractive target for cancer therapy. However, targeting c-Myc directly is …
Extraction methods, multiple biological activities, and related mechanisms of Momordica charantia polysaccharide: A review
J Liu, Y Guo, J Sun, Y Lei, M Guo, L Wang - International Journal of …, 2024 - Elsevier
Abstract Momordica Charantia Polysaccharide (MCP) is a key bioactive compound derived
from bitter melon fruit. This review summarizes the advancements in MCP research …
from bitter melon fruit. This review summarizes the advancements in MCP research …
Liraglutide Attenuates Diabetic Cardiomyopathy via the ILK/PI3K/AKT/PTEN Signaling Pathway in Rats with Streptozotocin-Induced Type 2 Diabetes Mellitus
SM Alobaid, RM Alshahrani, AS Alonazi… - Pharmaceuticals, 2024 - mdpi.com
One of the possible candidates for the treatment of diabetic cardiomyopathy is liraglutide, a
glucagon-like peptide-1 receptor (GLP1R) agonist. In this study, the impacts of liraglutide on …
glucagon-like peptide-1 receptor (GLP1R) agonist. In this study, the impacts of liraglutide on …
Momordica charantia nanoparticles promote mitochondria biogenesis in the pancreas of diabetic-induced rats: gene expression study
Background Mitochondria dysfunction is one of the clinical features of diabetes mellitus
(DM), which is a hallmark of insulin resistance (IR). This study investigates the therapeutic …
(DM), which is a hallmark of insulin resistance (IR). This study investigates the therapeutic …
Screening of compounds from Nigerian antidiabetic plants as protein tyrosine phosphatase 1B inhibitor
Several studies have established the antidiabetic properties of several traditional Nigerian
plants, but only limited studies have elucidated their mechanism of action. Protein tyrosine …
plants, but only limited studies have elucidated their mechanism of action. Protein tyrosine …