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The biology and function of exosomes in cancer
R Kalluri - The Journal of clinical investigation, 2016 - jci.org
Humans circulate quadrillions of exosomes at all times. Exosomes are a class of
extracellular vesicles released by all cells, with a size range of 40–150 nm and a lipid …
extracellular vesicles released by all cells, with a size range of 40–150 nm and a lipid …
[HTML][HTML] The regulatory role of microRNAs in breast cancer
HY Loh, BP Norman, KS Lai, NMANA Rahman… - International journal of …, 2019 - mdpi.com
MicroRNAs (miRNAs) are small non-coding RNA molecules which function as critical post-
transcriptional gene regulators of various biological functions. Generally, miRNAs negatively …
transcriptional gene regulators of various biological functions. Generally, miRNAs negatively …
[HTML][HTML] Exosomes as therapeutic drug carriers and delivery vehicles across biological membranes: current perspectives and future challenges
D Ha, N Yang, V Nadithe - Acta Pharmaceutica Sinica B, 2016 - Elsevier
Exosomes are small intracellular membrane-based vesicles with different compositions that
are involved in several biological and pathological processes. The exploitation of exosomes …
are involved in several biological and pathological processes. The exploitation of exosomes …
The promising role of miR-21 as a cancer biomarker and its importance in RNA-based therapeutics
D Bautista-Sánchez, C Arriaga-Canon… - … therapy Nucleic acids, 2020 - cell.com
MicroRNAs are small noncoding transcripts that posttranscriptionally regulate gene
expression via base-pairing complementarity. Their role in cancer can be related to tumor …
expression via base-pairing complementarity. Their role in cancer can be related to tumor …
Biological functions and current advances in isolation and detection strategies for exosome nanovesicles
Abstract Exosomes are nanoscale (≈ 30–150 nm) extracellular vesicles of endocytic origin
that are shed by most types of cells and circulate in bodily fluids. Exosomes carry a specific …
that are shed by most types of cells and circulate in bodily fluids. Exosomes carry a specific …
Tumor-derived exosomes and their role in cancer progression
TL Whiteside - Advances in clinical chemistry, 2016 - Elsevier
Tumor cells actively produce, release, and utilize exosomes to promote tumor growth.
Mechanisms through which tumor-derived exosomes subserve the tumor are under intense …
Mechanisms through which tumor-derived exosomes subserve the tumor are under intense …
Exosomes in cancer: small particle, big player
X Zhang, X Yuan, H Shi, L Wu, H Qian, W Xu - Journal of hematology & …, 2015 - Springer
Exosomes have emerged as a novel mode of intercellular communication. Exosomes can
shuttle bioactive molecules including proteins, DNA, mRNA, as well as non-coding RNAs …
shuttle bioactive molecules including proteins, DNA, mRNA, as well as non-coding RNAs …
MicroRNAs: new biomarkers for diagnosis, prognosis, therapy prediction and therapeutic tools for breast cancer
Dysregulation of microRNAs (miRNAs) is involved in the initiation and progression of
several human cancers, including breast cancer (BC), as strong evidence has been found …
several human cancers, including breast cancer (BC), as strong evidence has been found …
Emerging roles of exosomes in normal and pathological conditions: new insights for diagnosis and therapeutic applications
J De Toro, L Herschlik, C Waldner… - Frontiers in …, 2015 - frontiersin.org
From the time when they were first described in the 1970s by the group of Johnstone and
Stahl, exosomes are a target of constant research. Exosomes belong to the family of …
Stahl, exosomes are a target of constant research. Exosomes belong to the family of …
[HTML][HTML] Methodologies to isolate and purify clinical grade extracellular vesicles for medical applications
The use of extracellular vesicles (EV) in nano drug delivery has been demonstrated in many
previous studies. In this study, we discuss the sources of extracellular vesicles, including …
previous studies. In this study, we discuss the sources of extracellular vesicles, including …