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Hepatic stellate cells–from past till present: morphology, human markers, human cell lines, behavior in normal and liver pathology
RT Sufleţel, CS Melincovici, BA Gheban… - … of Morphology and …, 2021 - pmc.ncbi.nlm.nih.gov
Hepatic stellate cell (HSC), initially analyzed by von Kupffer, in 1876, revealed to be an
extraordinary mesenchymal cell, essential for both hepatocellular function and lesions …
extraordinary mesenchymal cell, essential for both hepatocellular function and lesions …
Multiscale coupling of an agent-based model of tissue fibrosis and a logic-based model of intracellular signaling
Wound healing and fibrosis following myocardial infarction (MI) is a dynamic process
involving many cell types, extracellular matrix (ECM), and inflammatory cues. As both …
involving many cell types, extracellular matrix (ECM), and inflammatory cues. As both …
Occult hepatitis B virus infection and liver fibrosis in chinese patients
X Tang, L Yang, P Zhang, C Wang, S Luo… - The Journal of …, 2023 - academic.oup.com
Background The impact of hepatitis B surface antigen (HBsAg)–negative/hepatitis B virus
(HBV) DNA–positive occult HBV infection (OBI) on the severity of liver fibrosis remains …
(HBV) DNA–positive occult HBV infection (OBI) on the severity of liver fibrosis remains …
Mathematical modeling for the combination treatment of IFN-γ and anti-PD-1 in cancer immunotherapy
KL Liao, KD Watt - Mathematical Biosciences, 2022 - Elsevier
When the immune-checkpoint programmed death-1 (PD-1) binds to its ligand programmed
death ligand 1 (PD-L1) to form the complex PD-1-PD-L1, this complex inactivates immune …
death ligand 1 (PD-L1) to form the complex PD-1-PD-L1, this complex inactivates immune …
Mathematical modeling of hepatitis B virus infection for antiviral therapy using LHAM
M Aniji, N Kavitha, S Balamuralitharan - Advances in Difference Equations, 2020 - Springer
Anti-viral therapy is comparatively very effective for patients who get affected by the hepatitis
B virus. It is of prime importance to understand the different relations among the viruses …
B virus. It is of prime importance to understand the different relations among the viruses …
Optimal timing of steroid initiation in response to CTLA-4 antibody in metastatic cancer: A mathematical model
N Siewe, A Friedman - Plos one, 2022 - journals.plos.org
Immune checkpoint inhibitors, introduced in recent years, have revolutionized the treatment
of many cancers. However, the toxicity associated with this therapy may cause severe …
of many cancers. However, the toxicity associated with this therapy may cause severe …
IL-27 in combination with anti-PD-1 can be anti-cancer or pro-cancer
KL Liao, XF Bai, A Friedman - Journal of Theoretical Biology, 2024 - Elsevier
Abstract Interleukin-27 (IL-27) is known to play opposing roles in immunology. The present
paper considers, specifically, the role IL-27 plays in cancer immunotherapy when combined …
paper considers, specifically, the role IL-27 plays in cancer immunotherapy when combined …
Travelling waves of a nonlinear reaction-diffusion model of the hepatitis B virus
BT Mbopda, S Issa, R Guiem, SCO Noutchie… - The European Physical …, 2023 - Springer
A mathematical model of viral hepatitis B that takes into account healthy cells, infected cells
and free viruses is studied in this paper. This model takes into account spatial mobility of all …
and free viruses is studied in this paper. This model takes into account spatial mobility of all …
[HTML][HTML] Improving the hepatitis viral transmission model's dynamics by vaccination and contrasting it with the fractional-order model
RM Yaseen, AA Mohsen, HF AL-Husseiny… - … Differential Equations in …, 2024 - Elsevier
We investigate mathematical models of the Hepatitis B and C viruses in the study,
considering vaccination effects into account. By utilising fractional and ordinary differential …
considering vaccination effects into account. By utilising fractional and ordinary differential …
A mathematical model of the multiple sclerosis plaque
N Moise, A Friedman - Journal of theoretical biology, 2021 - Elsevier
Multiple sclerosis is an autoimmune disease that affects white matter in the central nervous
system. It is one of the primary causes of neurological disability among young people. Its …
system. It is one of the primary causes of neurological disability among young people. Its …