Immunological memory to SARS‐CoV‐2 infection and COVID‐19 vaccines

A Sette, S Crotty - Immunological reviews, 2022 - Wiley Online Library
Immunological memory is the basis of protective immunity provided by vaccines and
previous infections. Immunological memory can develop from multiple branches of the …

A quest for universal anti-SARS-CoV-2 T cell assay: systematic review, meta-analysis, and experimental validation

A Binayke, A Zaheer, S Vishwakarma, S Singh… - npj Vaccines, 2024 - nature.com
Abstract Measuring SARS-CoV-2-specific T cell responses is crucial to understanding an
individual's immunity to COVID-19. However, high inter-and intra-assay variability make it …

[HTML][HTML] Comparing the immune abnormalities in MIS-C to healthy children and those with inflammatory disease reveals distinct inflammatory cytokine production and …

C Butters, N Benede, T Moyo-Gwete, SI Richardson… - Clinical …, 2024 - Elsevier
Multisystem inflammatory syndrome in children (MIS-C) is a severe, hyperinflammatory
disease that occurs after exposure to severe acute respiratory syndrome coronavirus 2 …

[HTML][HTML] Distinct T cell polyfunctional profile in SARS-CoV-2 seronegative children associated with endemic human coronavirus cross-reactivity

N Benede, MB Tincho, A Walters, V Subbiah, A Ngomti… - Iscience, 2024 - cell.com
SARS-CoV-2 infection in children typically results in asymptomatic or mild disease. There is
a paucity of studies on SARS-CoV-2 antiviral immunity in African children. We investigated …

The MegaPool Approach to Characterize Adaptive CD4+ and CD8+ T Cell Responses

R da Silva Antunes, D Weiskopf, J Sidney… - Current …, 2023 - Wiley Online Library
Epitopes recognized by T cells are a collection of short peptide fragments derived from
specific antigens or proteins. Immunological research to study T cell responses is hindered …

[HTML][HTML] Nucleic acid biomarkers of immune response and cell and tissue damage in children with COVID-19 and MIS-C

CJ Loy, A Sotomayor-Gonzalez, V Servellita… - Cell Reports …, 2023 - cell.com
Differential host responses in coronavirus disease 2019 (COVID-19) and multisystem
inflammatory syndrome in children (MIS-C) remain poorly characterized. Here, we use next …

Immune responses during COVID-19 breakthrough cases in vaccinated children and adolescents

D Rivera-Pérez, C Méndez, B Diethelm-Varela… - Frontiers in …, 2024 - frontiersin.org
Background Vaccine effectiveness against SARS-CoV-2 infection has been somewhat
limited due to the widespread dissemination of the Omicron variant, its subvariants, and the …

[HTML][HTML] Serologic responses to COVID-19 vaccination in children with history of multisystem inflammatory syndrome (MIS-C)

MA Perez, HM Hsiao, X Chen, A Kunkel, N Baida… - Vaccine, 2023 - Elsevier
Understanding the serological responses to COVID-19 vaccination in children with history of
MIS-C could inform vaccination recommendations. We prospectively enrolled seven children …

Routine SARS‐CoV‐2 vaccination for all children

K De Paris, SR Permar - Immunological reviews, 2022 - Wiley Online Library
The SARS‐CoV‐2 pandemic has resulted in unprecedented health and economic losses.
Children generally present with less severe disease from this virus compared with adults, yet …

Infant rhesus macaques immunized against SARS-CoV-2 are protected against heterologous virus challenge 1 year later

EC Milligan, K Olstad, CA Williams, M Mallory… - Science Translational …, 2022 - science.org
The US Food and Drug Administration only gave emergency use authorization of the
BNT162b2 and mRNA-1273 SARS-CoV-2 vaccines for infants 6 months and older in June …