Pathogenesis of systemic sclerosis

D Pattanaik, M Brown, BC Postlethwaite… - Frontiers in …, 2015 - frontiersin.org
Systemic scleroderma (SSc) is one of the most complex systemic autoimmune diseases. It
targets the vasculature, connective tissue-producing cells (namely fibroblasts/myofibroblasts …

Mortality in systemic sclerosis: an international meta-analysis of individual patient data

JPA Ioannidis, PG Vlachoyiannopoulos… - The American journal of …, 2005 - Elsevier
PURPOSE: Studies on mortality associated with systemic sclerosis have been limited by
small sample sizes. We aimed to obtain large-scale evidence on survival outcomes and …

Prevalence, incidence, survival, and disease characteristics of systemic sclerosis in a large US population

MD Mayes, JV Lacey Jr… - … : Official Journal of …, 2003 - Wiley Online Library
Objective To estimate the prevalence, incidence, survival, and disease characteristics of
systemic sclerosis (SSc) in the Detroit tricounty area. Methods A census of SSc cases for the …

[BOOK][B] SPEC-Rheumatology, 12-Month Access, eBook

MC Hochberg, EM Gravallese, JS Smolen… - 2022 - books.google.com
Covering both the scientific basis of rheumatology and practical, clinical information for
rheumatologists and trainees, Rheumatology, 8th Edition, remains a leading text in this fast …

The clinical relevance of autoantibodies in scleroderma

KT Ho, JD Reveille - Arthritis Res Ther, 2003 - Springer
Scleroderma (systemic sclerosis) is associated with several autoantibodies, each of which is
useful in the diagnosis of affected patients and in determining their prognosis. Anti …

Clinical correlations with dermatomyositis-specific autoantibodies in adult Japanese patients with dermatomyositis: a multicenter cross-sectional study

Y Hamaguchi, M Kuwana, K Hoshino… - Archives of …, 2011 - jamanetwork.com
Objective To clarify the association of clinical and prognostic features with dermatomyositis
(DM)-specific autoantibodies (Abs) in adult Japanese patients with DM. Design …

The pathogenesis of systemic sclerosis

TR Katsumoto, ML Whitfield… - Annual Review of …, 2011 - annualreviews.org
Systemic sclerosis (SSc), also known as scleroderma, is a rare connective tissue disease
characterized by vascular and immune dysfunction, leading to fibrosis that can damage …

Systemic lupus erythematosus in three ethnic groups. XII. Risk factors for lupus nephritis after diagnosis

HM Bastian, JM Roseman, G McGwin Jr, GS Alarcon… - Lupus, 2002 - journals.sagepub.com
The purpose of this study was to determine the cumulative incidence of lupus nephritis (LN)
and the factors predictive of its occurrencein a multiethnic systemic lupus erythematosus …

Autoantibodies in systemic sclerosis

S Mehra, J Walker, K Patterson, MJ Fritzler - Autoimmunity reviews, 2013 - Elsevier
Autoantibodies directed against a variety of nuclear, cytoplasmic and extracellular
autoantigens are a serological hallmark of systemic sclerosis. This review provides an …

Familial occurrence frequencies and relative risks for systemic sclerosis (scleroderma) in three United States cohorts

FC Arnett, M Cho, S Chatterjee… - … : Official Journal of …, 2001 - Wiley Online Library
Objective To determine the frequency with which scleroderma (systemic sclerosis; SSc)
recurs in families and the familial relative risk (λ) in the US. Methods Family histories of SSc …