Recently, feature selection and dimensionality reduction have become fundamental tools for
many data mining tasks, especially for processing high-dimensional data such as gene …

With the rapid advances of various high-throughput technologies, generation of '-omics' data
is commonplace in almost every biomedical field. Effective data management and analytical …

Lung cancer is the world's leading cause of cancer death and shows strong ancestry
disparities. By sequencing and assembling a large genomic and transcriptomic dataset of …

Malignant transformation can result in melanoma cells that resemble different stages of their
embryonic development. Our gene expression analysis of human melanoma cell lines and …

Background Copper ions are essential for cellular physiology. Cuproptosis is a novel
method of copper-dependent cell death, and the cuproptosis-based signature for glioma …

Rationale: Accumulating evidence demonstrated that long noncoding RNAs (lncRNAs)
involved in the regulation of the immune system and displayed a cell-type-specific pattern in …

Long noncoding ribonucleic acids (RNAs; lncRNAs) have been associated with cancer
immunity regulation. However, the roles of immune cell-specific lncRNAs in glioblastoma …

Intrahepatic cholangiocarcinoma (ICC) and hepatocellular carcinoma (HCC) are clinically
disparate primary liver cancers with etiological and biological heterogeneity. We identified …

Recent studies identified a poor-prognosis stem/serrated/mesenchymal (SSM)
transcriptional subtype of colorectal cancer (CRC). We noted that genes upregulated in this …

Glioblastoma (GBM) is the most malignant and lethal intracranial tumor, with extremely
limited treatment options. Immunotherapy has been widely studied in GBM, but none can …