Phage therapy in the postantibiotic era

FL Gordillo Altamirano, JJ Barr - Clinical microbiology reviews, 2019 - journals.asm.org
Antibiotic resistance is arguably the biggest current threat to global health. An increasing
number of infections are becoming harder or almost impossible to treat, carrying high …

Endolysin, a promising solution against antimicrobial resistance

M Rahman, W Wang, Q Sun, JA Shah, C Li, Y Sun, Y Li… - Antibiotics, 2021 - mdpi.com
Antimicrobial resistance (AMR) is a global crisis for human public health which threatens the
effective prevention and control of ever-increasing infectious diseases. The advent of …

[HTML][HTML] Treating bacterial infections with bacteriophage-based enzybiotics: in vitro, in vivo and clinical application

KM Danis-Wlodarczyk, DJ Wozniak, ST Abedon - Antibiotics, 2021 - mdpi.com
Over the past few decades, we have witnessed a surge around the world in the emergence
of antibiotic-resistant bacteria. This global health threat arose mainly due to the overuse and …

Bacteriophage therapy for drug-resistant Staphylococcus aureus infections

K Liu, C Wang, X Zhou, X Guo, Y Yang… - Frontiers in Cellular …, 2024 - frontiersin.org
Drug-resistant Staphylococcus aureus stands as a prominent pathogen in nosocomial and
community-acquired infections, capable of inciting various infections at different sites in …

[HTML][HTML] Multiple roles for cytokines in atopic dermatitis: from pathogenic mediators to endotype-specific biomarkers to therapeutic targets

L Fania, G Moretta, F Antonelli, E Scala… - International Journal of …, 2022 - mdpi.com
Atopic dermatitis (AD) is one of the most common chronic inflammatory skin diseases, which
generally presents with intense itching and recurrent eczematous lesions. AD affects up to …

The preclinical and clinical progress of bacteriophages and their lytic enzymes: the parts are easier than the whole

K Abdelkader, H Gerstmans, A Saafan, T Dishisha… - Viruses, 2019 - mdpi.com
The therapeutic potential of phages has been considered since their first identification more
than a century ago. The evident concept of using a natural predator to treat bacterial …

[HTML][HTML] Medical device-associated healthcare infections: sterilization and the potential of novel biological approaches to ensure patient safety

M Garvey - International Journal of Molecular Sciences, 2023 - mdpi.com
Healthcare-associated infections caused by multi-drug-resistant pathogens are increasing
globally, and current antimicrobial options have limited efficacy against these robust …

Discovery of antimicrobial lysins from the “dark matter” of uncharacterized phages using artificial intelligence

Y Zhang, R Li, G Zou, Y Guo, R Wu, Y Zhou… - Advanced …, 2024 - Wiley Online Library
The rapid rise of antibiotic resistance and slow discovery of new antibiotics have threatened
global health. While novel phage lysins have emerged as potential antibacterial agents …

Linker-Improved Chimeric Endolysin Selectively Kills Staphylococcus aureus In Vitro, on Reconstituted Human Epidermis, and in a Murine Model of Skin Infection

F Eichenseher, BL Herpers, P Badoux… - Antimicrobial Agents …, 2022 - journals.asm.org
Staphylococcus aureus causes a broad spectrum of diseases in humans and animals. It is
frequently associated with inflammatory skin disorders such as atopic dermatitis, where it …

Staphylococcus aureus: an underestimated factor in the pathogenesis of atopic dermatitis?

L Blicharz, L Rudnicka, Z Samochocki - Advances in Dermatology and …, 2019 - termedia.pl
Atopic dermatitis is a common, recurrent pruritic dermatosis with a complex pathogenesis. It
has been associated with disordered patterns of immunological response and impaired …