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How addictive are gabapentin and pregabalin? A systematic review
In the last ten years, gabapentin and pregabalin have been becoming dispensed broadly
and sold on black markets, thereby, exposing millions to potential side-effects. Meanwhile …
and sold on black markets, thereby, exposing millions to potential side-effects. Meanwhile …
[HTML][HTML] Neurotransmitters as food supplements: the effects of GABA on brain and behavior
Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the human
cortex. The food supplement version of GABA is widely available online. Although many …
cortex. The food supplement version of GABA is widely available online. Although many …
Brain GABA levels across psychiatric disorders: A systematic literature review and meta‐analysis of 1H‐MRS studies
RR Schür, LWR Draisma, JP Wijnen… - Human brain …, 2016 - Wiley Online Library
The inhibitory gamma‐aminobutyric acid (GABA) system is involved in the etiology of most
psychiatric disorders, including schizophrenia, autism spectrum disorder (ASD) and major …
psychiatric disorders, including schizophrenia, autism spectrum disorder (ASD) and major …
Efficacy of gabapentin for the treatment of alcohol use disorder in patients with alcohol withdrawal symptoms: a randomized clinical trial
RF Anton, P Latham, K Voronin, S Book… - JAMA internal …, 2020 - jamanetwork.com
Importance Although an estimated 30 million people meet criteria for alcohol use disorder
(AUD), few receive appropriate pharmacotherapy. A more personalized, symptom-specific …
(AUD), few receive appropriate pharmacotherapy. A more personalized, symptom-specific …
Neuroimaging of pain: human evidence and clinical relevance of central nervous system processes and modulation
Pain is a highly complex and individual experience with biological, psychological and social
(biopsychosocial) contributions. Pain is associated with activity within the nervous system …
(biopsychosocial) contributions. Pain is associated with activity within the nervous system …
[HTML][HTML] Brain GABA and glutamate levels across pain conditions: A systematic literature review and meta-analysis of 1H-MRS studies using the MRS-Q quality …
Background A proposed mechanism of chronic pain is dysregulation between the main
inhibitory (GABA) and excitatory (glutamate) neurometabolites of the central nervous system …
inhibitory (GABA) and excitatory (glutamate) neurometabolites of the central nervous system …
Functional MRS studies of GABA and glutamate/Glx–A systematic review and meta-analysis
Functional magnetic resonance spectroscopy (fMRS) can be used to investigate
neurometabolic responses to external stimuli in-vivo, but findings are inconsistent. We …
neurometabolic responses to external stimuli in-vivo, but findings are inconsistent. We …
Misuse and abuse of pregabalin and gabapentin: cause for concern?
Gabapentinoids (eg pregabalin and gabapentin) are widely used in neurology, psychiatry
and primary healthcare but are increasingly being reported as possessing a potential for …
and primary healthcare but are increasingly being reported as possessing a potential for …
[PDF][PDF] Pregabalin rectifies aberrant brain chemistry, connectivity, and functional response in chronic pain patients
Background: Chronic pain remains a significant challenge for modern health care as its
pathologic mechanisms are largely unknown and preclinical animal models suffer from …
pathologic mechanisms are largely unknown and preclinical animal models suffer from …
Neurotransmitter deficits from frontotemporal lobar degeneration
Frontotemporal lobar degeneration causes a spectrum of complex degenerative disorders
including frontotemporal dementia, progressive supranuclear palsy and corticobasal …
including frontotemporal dementia, progressive supranuclear palsy and corticobasal …