Integrating mechanism-based modeling with biomedical imaging to build practical digital twins for clinical oncology
Digital twins employ mathematical and computational models to virtually represent a
physical object (eg, planes and human organs), predict the behavior of the object, and …
physical object (eg, planes and human organs), predict the behavior of the object, and …
Hemodynamic modeling, medical imaging, and machine learning and their applications to cardiovascular interventions
Cardiovascular disease is a deadly global health crisis that carries a substantial financial
burden. Innovative treatment and management of cardiovascular disease straddles …
burden. Innovative treatment and management of cardiovascular disease straddles …
[HTML][HTML] Patient-specific modeling of blood flow in the coronary arteries
Patient-specific models of blood flow in the coronary arteries have entered clinical practice
worldwide to aid in the diagnosis and management of heart disease. This technology …
worldwide to aid in the diagnosis and management of heart disease. This technology …
Analysis of finite element and finite volume methods for fluid-structure interaction simulation of blood flow in a real stenosed artery
This paper presents a qualitative and quantitative comparison between the finite element
and the finite volume methods for the fluid-structure interaction simulation of blood flow …
and the finite volume methods for the fluid-structure interaction simulation of blood flow …
Clinical impact of computational heart valve models
This paper provides a review of engineering applications and computational methods used
to analyze the dynamics of heart valve closures in healthy and diseased states …
to analyze the dynamics of heart valve closures in healthy and diseased states …
Attention-based multi-fidelity machine learning model for fractional flow reserve assessment
Abstract Coronary Artery Disease (CAD) is one of the most common forms of heart disease,
caused by a buildup of atherosclerotic plaque in the coronary arteries. When this buildup is …
caused by a buildup of atherosclerotic plaque in the coronary arteries. When this buildup is …
Effects of non-Newtonian viscosity on arterial and venous flow and transport
It is well known that blood exhibits non-Newtonian viscosity, but it is generally modeled as a
Newtonian fluid. However, in situations of low shear rate, the validity of the Newtonian …
Newtonian fluid. However, in situations of low shear rate, the validity of the Newtonian …
Patient‐specific computational modeling of endovascular aneurysm repair: State of the art and future directions
Endovascular aortic repair (EVAR) has become the preferred intervention option for aortic
aneurysms and dissections. This is because EVAR is much less invasive than the alternative …
aneurysms and dissections. This is because EVAR is much less invasive than the alternative …
Comparative study of human and murine aortic biomechanics and hemodynamics in vascular aging
Introduction: Aging has many effects on the cardiovascular system, including changes in
structure (aortic composition, and thus stiffening) and function (increased proximal blood …
structure (aortic composition, and thus stiffening) and function (increased proximal blood …
Impact of TAVR on coronary artery hemodynamics using clinical measurements and image‐based patient‐specific in silico modeling
In recent years, transcatheter aortic valve replacement (TAVR) has become the leading
method for treating aortic stenosis. While the procedure has improved dramatically in the …
method for treating aortic stenosis. While the procedure has improved dramatically in the …