The effects of neutrophil-generated hypochlorous acid and other hypohalous acids on host and pathogens
Neutrophils are predominant immune cells that protect the human body against infections by
deploying sophisticated antimicrobial strategies including phagocytosis of bacteria and …
deploying sophisticated antimicrobial strategies including phagocytosis of bacteria and …
The ArcAB two-component system: function in metabolism, redox control, and infection
AN Brown, MT Anderson, MA Bachman… - Microbiology and …, 2022 - Am Soc Microbiol
ArcAB, also known as the Arc system, is a member of the two-component system family of
bacterial transcriptional regulators and is composed of sensor kinase ArcB and response …
bacterial transcriptional regulators and is composed of sensor kinase ArcB and response …
Tracking insertion mutants within libraries by deep sequencing and a genome-wide screen for Haemophilus genes required in the lung
JD Gawronski, SMS Wong… - Proceedings of the …, 2009 - National Acad Sciences
Rapid genome-wide identification of genes required for infection would expedite studies of
bacterial pathogens. We developed genome-scale “negative selection” technology that …
bacterial pathogens. We developed genome-scale “negative selection” technology that …
Environmental adaptation and diversification of bacterial two-component systems
Bacterial two-component systems (TCS) are versatile signaling mechanisms that govern
cellular responses to diverse environmental cues. These systems rely on phosphoryl-group …
cellular responses to diverse environmental cues. These systems rely on phosphoryl-group …
Klebsiella pneumoniae causes bacteremia using factors that mediate tissue-specific fitness and resistance to oxidative stress
CL Holmes, AE Wilcox, V Forsyth, SN Smith… - PLoS …, 2023 - journals.plos.org
Gram-negative bacteremia is a major cause of global morbidity involving three phases of
pathogenesis: initial site infection, dissemination, and survival in the blood and filtering …
pathogenesis: initial site infection, dissemination, and survival in the blood and filtering …
ArcS, the Cognate Sensor Kinase in an Atypical Arc System of Shewanella oneidensis MR-1
J Lassak, AL Henche, L Binnenkade… - Applied and …, 2010 - Am Soc Microbiol
The availability of oxygen is a major environmental factor for many microbes, in particular for
bacteria such as Shewanella species, which thrive in redox-stratified environments. One of …
bacteria such as Shewanella species, which thrive in redox-stratified environments. One of …
Towards development of electrogenetics using electrochemically active bacteria
A Hirose, A Kouzuma, K Watanabe - Biotechnology advances, 2019 - Elsevier
Owing to the ability for efficient electric interaction with electrodes, electrochemically active
bacteria (EAB) attract considerable attention in biotechnology. These bacteria are involved …
bacteria (EAB) attract considerable attention in biotechnology. These bacteria are involved …
Mechanisms underlying interactions between two abundant oral commensal bacteria
D Perera, A McLean, V Morillo-López… - The ISME …, 2022 - academic.oup.com
Complex polymicrobial biofilm communities are abundant in nature particularly in the human
oral cavity where their composition and fitness can affect health. While the study of these …
oral cavity where their composition and fitness can affect health. While the study of these …
Microbial oxidative stress response: novel insights from environmental facultative anaerobic bacteria
H Fu, J Yuan, H Gao - Archives of biochemistry and biophysics, 2015 - Elsevier
Facultative bacteria can grow under either oxic or anoxic conditions. While oxygen provides
substantial advantages in energy yield by respiration, it can become life-threatening …
substantial advantages in energy yield by respiration, it can become life-threatening …
The ArcAB two-component regulatory system promotes resistance to reactive oxygen species and systemic infection by Salmonella Typhimurium
Salmonella enterica Serovar Typhimurium (S. Typhimurium) is an intracellular bacterium
that overcomes host immune system barriers for successful infection. The bacterium …
that overcomes host immune system barriers for successful infection. The bacterium …