This work presents a review of the main deterministic mixed‐integer nonlinear programming
(MINLP) solution methods for problems with convex and nonconvex functions. An overview …

Process intensification (PI) is an emerging concept in chemical engineering that describes
the design innovations that lead to significant shrinkage in size and boost in efficiency of a …

Crude distillation, with a long history of research and commercial improvements, is
perceived to be a mature separation technology with minimal scope of improvement. By …

Reaction/distillation matrix for reactive distillation is one of the systematic algorithms to
generate different possible sequences of distillation columns containing reactive distillation …

The design of thermally coupled distillation sequences explicitly including the possibility of
divided wall columns (DWC) is described. A DWC with a single wall can be considered …

This study presents a novel stochastic optimization method for the efficient synthesis of large‐
scale nonsharp distillation systems, where heat integration and thermal coupling can be …

This study demonstrates the efficacy of a short-cut method such as the Global Minimization
Algorithm (GMA), that uses assumptions of ideal mixtures, constant molar overflow (CMO) …

An easy‐to‐use matrix‐based method for the systematic synthesis of distillation
configurations using less than n‐1 columns to separate any zeotropic n‐component feed …

NGL fractionation is one of the most energy-intensive facilities in hydrocarbon processing
plants playing an important role in the petrochemical supply chain. Innovative schemes for …

Prior to detailed process design, it is vital to first generate a good flowsheet that meets
particular objective. This is particularly the case in bio-based materials and products, where …