Antibiotic resistance has become a global public health priority. Polymyxins, a family of
cationic polypeptide antibiotics, act as a final line of refuge against severe infections by …

Colistin drug resistance is an emerging public health threat worldwide. The adaptability,
existence and spread of colistin drug resistance in multiple reservoirs and ecological …

To understand the dynamics behind the worldwide spread of the mcr-1 gene, we determined
the population structure of Escherichia coli and of mobile genetic elements (MGEs) carrying …

A mobile colistin resistance gene mcr was first reported in 2016 in China and has since
been found with increasing prevalence across South-East Asia. Here we survey the …

Background Mobile colistin resistance (mcr) genes modify Lipid A molecules of the
lipopolysaccharide, changing the overall charge of the outer membrane. Results and …

The global rise in antibiotic resistance in bacteria poses a major challenge in treating
infectious diseases. Polymyxins (eg, polymyxin B and colistin) are last-resort antibiotics …

The emergence of plasmid-mediated colistin resistance (mcr genes) threatens the
effectiveness of polymyxins, which are last-resort drugs to treat infections by multidrug-and …

Abstract Cubic phase Li 7 La 3 Zr 2 O 12 (LLZO), a member of the Li–Garnet family, is a
promising solid electrolyte and has been widely studied in recent years. However, LLZO …

Although aprotic Li-air batteries offer an attractive option for achieving ultrahigh energy
density of electrochemical energy storage devices, the now-established system has so far …

The mcr-1 (mobile colistin resistance 1) gene, which encodes phosphoethanolamine
transferase, has been recently identified as a source of acquired resistance to polymyxins in …