Fluorescent dyes based on rhodamine derivatives for bioimaging and therapeutics: recent progress, challenges, and prospects

S Zeng, X Liu, YS Kafuti, H Kim, J Wang… - Chemical Society …, 2023 - pubs.rsc.org
Since their inception, rhodamine dyes have been extensively applied in biotechnology as
fluorescent markers or for the detection of biomolecules owing to their good optical physical …

Recent strategies to develop innovative photosensitizers for enhanced photodynamic therapy

TC Pham, VN Nguyen, Y Choi, S Lee, J Yoon - Chemical reviews, 2021 - ACS Publications
This review presents a robust strategy to design photosensitizers (PSs) for various species.
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …

Acceptor Planarization and Donor Rotation: A Facile Strategy for Realizing Synergistic Cancer Phototherapy via Type I PDT and PTT

L Feng, C Li, L Liu, Z Wang, Z Chen, J Yu, W Ji… - ACS …, 2022 - ACS Publications
Tumor hypoxia seriously impairs the therapeutic outcomes of type II photodynamic therapy
(PDT), which is highly dependent upon tissue oxygen concentration. Herein, a facile strategy …

Massively evoking immunogenic cell death by focused mitochondrial oxidative stress using an AIE luminogen with a twisted molecular structure

C Chen, X Ni, S Jia, Y Liang, X Wu, D Kong… - Advanced …, 2019 - Wiley Online Library
Immunogenic cell death (ICD) provides momentous theoretical principle for modern cancer
immunotherapy. However, the currently available ICD inducers are still very limited and …

Advances in the application of metal oxide nanozymes in tumor detection and treatment

C Cheng, H Wang, J Zhao, Y Wang, G Zhao… - Colloids and Surfaces B …, 2024 - Elsevier
Natural enzymes play an important role to support the regular life activities of the human
body. However, the application conditions of natural enzymes are harsh and there are …

Ratiometric optical nanoprobes enable accurate molecular detection and imaging

X Huang, J Song, BC Yung, X Huang… - Chemical Society …, 2018 - pubs.rsc.org
Exploring and understanding biological and pathological changes are of great significance
for early diagnosis and therapy of diseases. Optical sensing and imaging approaches have …

Near‐infrared photodynamic chemiluminescent probes for cancer therapy and metastasis detection

J Huang, C Zhang, X Wang, X Wei… - Angewandte Chemie, 2023 - Wiley Online Library
There is growing interest in the development of chemiluminescence (CL) probes for
phototheranostics because of their minimized tissue autofluorescence. However, due to a …

Overcoming the Achilles' heel of photodynamic therapy

W Fan, P Huang, X Chen - Chemical Society Reviews, 2016 - pubs.rsc.org
Photodynamic therapy (PDT) has been applied to treat a wide range of medical conditions,
including wet age-related macular degeneration psoriasis, atherosclerosis, viral infection …

A mesoporous nanoenzyme derived from metal–organic frameworks with endogenous oxygen generation to alleviate tumor hypoxia for significantly enhanced …

D Wang, H Wu, WQ Lim, SZF Phua, P Xu… - Advanced …, 2019 - Wiley Online Library
Tumor hypoxia compromises the therapeutic efficiency of photodynamic therapy (PDT) as
the local oxygen concentration plays an important role in the generation of cytotoxic singlet …

Cancer cell membrane camouflaged cascade bioreactor for cancer targeted starvation and photodynamic therapy

SY Li, H Cheng, BR **e, WX Qiu, JY Zeng, CX Li… - ACS …, 2017 - ACS Publications
Selectively cuting off the nutrient supply and the metabolism pathways of cancer cells would
be a promising approach to improve the efficiency of cancer treatment. Here, a cancer …