Malaria remains a leading cause of death and disease in many tropical and subtropical
regions of the world. Due to the alarming spread of resistance to almost all available …

Apicomplexan parasites secrete contents of the rhoptries, club-shaped organelles in the
apical region, into host cells to permit their invasion and establishment of infection. The …

Successfully developed in 1976, the continuous in vitro culture of Plasmodium falciparum
has many applications in the field of malaria research. It has become an important …

The unprecedented rise in the number of new and emerging infectious diseases in the last
quarter century poses direct threats to human and wildlife health. The introduction to the …

Host iron deficiency is protective against severe malaria as the human malaria parasite
Plasmodium falciparum depends on bioavailable iron from its host to proliferate. The …

Identification of Plasmodium-resistance genes in malaria vectors remains an elusive goal
despite the recent availability of high-quality genomes of several mosquito vectors …

Despite a remarkable improvement in health care and continued drug discovery efforts,
malaria control efforts are continuously challenged by the emergence of drug-resistant …

Malaria is a parasitic disease caused by protozoan parasites from the genus Plasmodium.
Plasmodium falciparum is the most prevalent species worldwide and the causative agent of …

Apicomplexan parasites secrete the contents of rhoptries into host cells to permit their
invasion and establishment of an infectious niche. The rhoptry secretory apparatus (RSA) …

Malaria is a disease caused by Plasmodium parasites affecting millions of people globally.
Different strategies were applied throughout the years to decrease malaria burden, however …