Evolving concepts of the vulnerable atherosclerotic plaque and the vulnerable patient: implications for patient care and future research

P Gaba, BJ Gersh, J Muller, J Narula… - Nature Reviews …, 2023 - nature.com
Understanding the natural history of coronary artery atherosclerosis is necessary to
determine prognosis and prescribe effective therapies. Traditional management of coronary …

Role of endothelial shear stress in stent restenosis and thrombosis: pathophysiologic mechanisms and implications for clinical translation

KC Koskinas, YS Chatzizisis, AP Antoniadis… - Journal of the American …, 2012 - jacc.org
Restenosis and thrombosis are potentially fatal complications of coronary stenting with a
recognized multifactorial etiology. The effect of documented risk factors, however, cannot …

Incomplete stent apposition causes high shear flow disturbances and delay in neointimal coverage as a function of strut to wall detachment distance: implications for …

N Foin, JL Gutiérrez-Chico, S Nakatani… - Circulation …, 2014 - Am Heart Assoc
Background—Lack of re-endothelialization and neointimal coverage on stent struts has
been put forward as the main underlying mechanism leading to late stent thrombosis …

Biomechanical modeling to improve coronary artery bifurcation stenting: expert review document on techniques and clinical implementation

AP Antoniadis, P Mortier, G Kassab, G Dubini… - Cardiovascular …, 2015 - jacc.org
Abstract Treatment of coronary bifurcation lesions remains an ongoing challenge for
interventional cardiologists. Stenting of coronary bifurcations carries higher risk for in-stent …

Microstructure-based biomechanics of coronary arteries in health and disease

H Chen, GS Kassab - Journal of biomechanics, 2016 - Elsevier
Coronary atherosclerosis is the major cause of mortality and disability in developed nations.
A deeper understanding of mechanical properties of coronary arteries and hence their …

Hemodynamics in idealized stented coronary arteries: important stent design considerations

S Beier, J Ormiston, M Webster, J Cater… - Annals of biomedical …, 2016 - Springer
Stent induced hemodynamic changes in the coronary arteries are associated with higher
risk of adverse clinical outcome. The purpose of this study was to evaluate the impact of …

Vanguard Study: Initial experience with the new fourth generation Pipeline Vantage Flow Diverter (PVFD): 6-month results, technical and clinical considerations

L de Villiers, VC do Nascimento, L Domitrovic… - Journal of …, 2025 - jnis.bmj.com
Background The Pipeline Embolization Device has proven to be a safe and effective device
for the treatment of intracranial aneurysms. The Pipeline Vantage Flow Diverter (PVFD) with …

Fluid–structure interaction between pulsatile blood flow and a curved stented coronary artery on a beating heart: A four stent computational study

M Bukač, S Čanić, J Tambača, Y Wang - Computer methods in applied …, 2019 - Elsevier
This work focuses on fluid–structure interaction (FSI) between a curved (tortuous) coronary
artery with an implanted stent, pulsatile blood flow, and heart contractions. The goal is to …

Which diameter and angle rule provides optimal flow patterns in a coronary bifurcation?

Y Huo, G Finet, T Lefevre, Y Louvard, I Moussa… - Journal of …, 2012 - Elsevier
The branching angle and diameter ratio in epicardial coronary artery bifurcations are two
important determinants of atherogenesis. Murray's cubed diameter law and bifurcation angle …

The development of design and manufacture techniques for bioresorbable coronary artery stents

L Wang, L Jiao, S Pang, P Yan, X Wang, T Qiu - Micromachines, 2021 - mdpi.com
Coronary artery disease (CAD) is the leading killer of humans worldwide. Bioresorbable
polymeric stents have attracted a great deal of interest because they can treat CAD without …