Deadly proteomes: a practical guide to proteotranscriptomics of animal venoms

AA Walker, SD Robinson, BF Hamilton… - …, 2020 - Wiley Online Library
Animal venoms are renowned for their toxicity, biochemical complexity, and as a source of
compounds with potential applications in medicine, agriculture, and industry. Polypeptides …

[HTML][HTML] Addressing the global snakebite crisis with geo-spatial analyses–Recent advances and future direction

AFV Pintor, N Ray, J Longbottom, CA Bravo-Vega… - Toxicon: X, 2021 - Elsevier
Venomous snakebite is a neglected tropical disease that annually leads to hundreds of
thousands of deaths or long-term physical and mental ailments across the develo** world …

[HTML][HTML] Beyond the 'big four': Venom profiling of the medically important yet neglected Indian snakes reveals disturbing antivenom deficiencies

RRS Laxme, S Khochare, HF de Souza… - PLoS neglected …, 2019 - journals.plos.org
Background Snakebite in India causes the highest annual rates of death (46,000) and
disability (140,000) than any other country. Antivenom is the mainstay treatment of …

Phylogenetically diverse diets favor more complex venoms in North American pitvipers

ML Holding, JL Strickland… - Proceedings of the …, 2021 - National Acad Sciences
The role of natural selection in the evolution of trait complexity can be characterized by
testing hypothesized links between complex forms and their functions across species …

Coevolution of snake venom toxic activities and diet: Evidence that ecological generalism favours toxicological diversity

EL Davies, K Arbuckle - Toxins, 2019 - mdpi.com
Snake venom evolution is typically considered to be predominantly driven by diet-related
selection pressures. Most evidence for this is based on lethality to prey and non-prey …

Snake venom in context: neglected clades and concepts

TNW Jackson, H Jouanne, N Vidal - Frontiers in Ecology and …, 2019 - frontiersin.org
Despite the fact that venom is an intrinsically ecological trait, the ecological perspective has
been widely neglected in toxinological research. This neglect has hindered our …

[HTML][HTML] Promoting co-existence between humans and venomous snakes through increasing the herpetological knowledge base

A Malhotra, W Wüster, JB Owens, CW Hodges… - Toxicon: X, 2021 - Elsevier
Snakebite incidence at least partly depends on the biology of the snakes involved. However,
studies of snake biology have been largely neglected in favour of anthropic factors, with the …

Diet breadth mediates the prey specificity of venom potency in snakes

K Lyons, MM Dugon, K Healy - Toxins, 2020 - mdpi.com
Venoms are best known for their ability to incapacitate prey. In predatory groups, venom
potency is predicted to reflect ecological and evolutionary drivers relating to diet. While …

[HTML][HTML] Mutual enlightenment: A toolbox of concepts and methods for integrating evolutionary and clinical toxinology via snake venomics and the contextual stance

JJ Calvete, B Lomonte, AJ Saviola, F Bonilla, M Sasa… - Toxicon: X, 2021 - Elsevier
Snakebite envenoming is a neglected tropical disease that may claim over 100,000 human
lives annually worldwide. Snakebite occurs as the result of an interaction between a human …

[HTML][HTML] Genomic, transcriptomic, and epigenomic analysis of a medicinal snake, Bungarus multicinctus, to provides insights into the origin of Elapidae neurotoxins

J Xu, S Guo, X Yin, M Li, H Su, X Liao, Q Li, L Le… - … Pharmaceutica Sinica B, 2023 - Elsevier
The many-banded krait, Bungarus multicinctus, has been recorded as the animal resource
of **QianBaiHuaShe in the Chinese Pharmacopoeia. Characterization of its venoms …