Breast cancer (BC) is the second most fatal disease and is the prime cause of cancer allied
female deaths. BC is caused by aberrant tumor suppressor genes and oncogenes regulated …

Cancer biology involves complex, dynamic interactions between cancer cells and their
tissue microenvironments. Single-cell effects are critical drivers of clinical progression …

Mathematical modelling approaches have become increasingly abundant in cancer
research. The complexity of cancer is well suited to quantitative approaches as it provides …

Background Inflammation in the lung is the body's natural response to injury. It acts to
remove harmful stimuli such as pathogens, irritants, and damaged cells and initiate the …

Dihydroartemisinin (DHA) is an active metabolite of artemisinin and its derivatives (ARTs),
and it is an effective clinical drug widely used to treat malaria. Recently, the anticancer …

Artemisinins are a family of sesquiterpene trioxane lactone anti-malarial agents originally
derived from Artemisia annua L. The anti-malarial action of artemisinins involves the …

Mathematical modelling of the movement of animals, micro-organisms and cells is of great
relevance in the fields of biology, ecology and medicine. Movement models can take many …

Objective Aberrant expression of the immune checkpoint molecule, CD276, also known as
B7-H3, is associated with tumorigenesis. In this review, we aim to comprehensively describe …

Most cancers in humans are large, measuring centimetres in diameter, and composed of
many billions of cells. An equivalent mass of normal cells would be highly heterogeneous as …

The anti-tumor activity of the immune system is increasingly recognized as critical for the
mounting of a prolonged and effective response to cancer growth and invasion, and for …