Cancer cells usually show adaptations to their metabolism that facilitate their growth,
invasiveness, and metastasis. Therefore, reprogramming the energy metabolism is one of …

Metabolic activity of malignant cells is very different from that of their nontransformed
equivalents, which establishes metabolic reprogramming as an important hallmark of every …

Dissemination of ovarian cancer cells can lead to inoperable metastatic lesions in the bowel
and omentum that cause patient death. Here we show that LRRC15, a type-I 15-leucine–rich …

Tumor-derived exosomes participate in omental metastatic colonization of ovarian cancer by
inducing an adaptive response in the tumor microenvironment. However, cell–cell …

Although simple in structure, lysophosphatidic acid (LPA) is a potent bioactive lipid that
profoundly influences cellular signaling and function upon binding to G protein-coupled …

Lipids are biological molecules that play vital roles in all living organisms. They perform
many cellular functions, such as 1) forming cellular and subcellular membranes, 2) storing …

Cancer cells are dependent on glutamine for their metabolism and growth. Despite being
the most abundant amino acid in the blood, glutamine deprivation occurs in the core of the …

As one of the important cancer hallmarks, metabolism reprogramming, including lipid
metabolism alterations, occurs in tumor cells and the tumor microenvironment (TME). It plays …

Although the biological processes of organism under hypoxic stress had been elucidated,
the whole physiological changes of Saccharomyces cerevisiae are still unclear. In this work …

Glycerophospholipid signal and fatty acid metabolism are closely related to the occurrence
and progression of tumours, and metabolic reprogramming caused by hydrolytic enzymes …