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Recent advances in DNA origami-engineered nanomaterials and applications
DNA nanotechnology is a unique field, where physics, chemistry, biology, mathematics,
engineering, and materials science can elegantly converge. Since the original proposal of …
engineering, and materials science can elegantly converge. Since the original proposal of …
DNA origami-based protein networks: from basic construction to emerging applications
G Kong, M **ong, L Liu, L Hu, HM Meng, G Ke… - Chemical Society …, 2021 - pubs.rsc.org
Natural living systems are driven by delicate protein networks whose functions are precisely
controlled by many parameters, such as number, distance, orientation, and position …
controlled by many parameters, such as number, distance, orientation, and position …
Live-cell super-resolved PAINT imaging of piconewton cellular traction forces
Despite the vital role of mechanical forces in biology, it still remains a challenge to image
cellular force with sub-100-nm resolution. Here, we present tension points accumulation for …
cellular force with sub-100-nm resolution. Here, we present tension points accumulation for …
Infrared nanosensors of piconewton to micronewton forces
Mechanical force is an essential feature for many physical and biological processes,,,,,–,
and remote measurement of mechanical signals with high sensitivity and spatial resolution …
and remote measurement of mechanical signals with high sensitivity and spatial resolution …
Oriented triplex DNA as a synthetic receptor for transmembrane signal transduction
H Chen, S Zhou, K Ngocho, J Zheng, X He… - Nature …, 2024 - nature.com
Signal transduction across biological membranes enables cells to detect and respond to
diverse chemical or physical signals, and replicating these complex biological processes …
diverse chemical or physical signals, and replicating these complex biological processes …
Hydrogel-based molecular tension fluorescence microscopy for investigating receptor-mediated rigidity sensing
W Wang, W Chen, C Wu, C Zhang, J Feng, P Liu… - Nature …, 2023 - nature.com
Extracellular matrix (ECM) rigidity serves as a crucial mechanical cue impacting diverse
biological processes. However, understanding the molecular mechanisms of rigidity sensing …
biological processes. However, understanding the molecular mechanisms of rigidity sensing …
Periodically ordered, nuclease‐resistant DNA nanowires decorated with cell‐specific aptamers as selective theranostic agents
DNA nanostructures have shown potential in cancer therapy. However, their clinical
application is hampered by the difficulty to deliver them into cancer cells and susceptibility to …
application is hampered by the difficulty to deliver them into cancer cells and susceptibility to …
A modular spring-loaded actuator for mechanical activation of membrane proteins
How cells respond to mechanical forces by converting them into biological signals underlie
crucial cellular processes. Our understanding of mechanotransduction has been hindered …
crucial cellular processes. Our understanding of mechanotransduction has been hindered …
Astigmatic traction force microscopy (aTFM)
Quantifying small, rapidly progressing three-dimensional forces generated by cells remains
a major challenge towards a more complete understanding of mechanobiology. Traction …
a major challenge towards a more complete understanding of mechanobiology. Traction …
Ultrafast DNA sensors with DNA framework-bridged hybridization reactions
Intracellular DNA-based hybridization reactions generally occur under tension rather than in
free states, which are spatiotemporally controlled in physiological conditions. However, how …
free states, which are spatiotemporally controlled in physiological conditions. However, how …