Obtaining genetics insights from deep learning via explainable artificial intelligence

G Novakovsky, N Dexter, MW Libbrecht… - Nature Reviews …, 2023 - nature.com
Artificial intelligence (AI) models based on deep learning now represent the state of the art
for making functional predictions in genomics research. However, the underlying basis on …

Deciphering the multi-scale, quantitative cis-regulatory code

S Kim, J Wysocka - Molecular cell, 2023 - cell.com
Uncovering the cis-regulatory code that governs when and how much each gene is
transcribed in a given genome and cellular state remains a central goal of biology. Here, we …

Legalbench: A collaboratively built benchmark for measuring legal reasoning in large language models

N Guha, J Nyarko, D Ho, C Ré… - Advances in …, 2023 - proceedings.neurips.cc
The advent of large language models (LLMs) and their adoption by the legal community has
given rise to the question: what types of legal reasoning can LLMs perform? To enable …

Ethics and governance of trustworthy medical artificial intelligence

J Zhang, Z Zhang - BMC medical informatics and decision making, 2023 - Springer
Background The growing application of artificial intelligence (AI) in healthcare has brought
technological breakthroughs to traditional diagnosis and treatment, but it is accompanied by …

Multimodal deep learning for biomedical data fusion: a review

SR Stahlschmidt, B Ulfenborg… - Briefings in …, 2022 - academic.oup.com
Biomedical data are becoming increasingly multimodal and thereby capture the underlying
complex relationships among biological processes. Deep learning (DL)-based data fusion …

A guide to machine learning for biologists

JG Greener, SM Kandathil, L Moffat… - Nature reviews Molecular …, 2022 - nature.com
The expanding scale and inherent complexity of biological data have encouraged a growing
use of machine learning in biology to build informative and predictive models of the …

[HTML][HTML] High-throughput proteomics: a methodological mini-review

M Cui, C Cheng, L Zhang - Laboratory investigation, 2022 - Elsevier
Proteomics plays a vital role in biomedical research in the post-genomic era. With the
technological revolution and emerging computational and statistic models, proteomic …

[HTML][HTML] Computer-aided drug design and drug discovery: a prospective analysis

SK Niazi, Z Mariam - Pharmaceuticals, 2023 - mdpi.com
In the dynamic landscape of drug discovery, Computer-Aided Drug Design (CADD) emerges
as a transformative force, bridging the realms of biology and technology. This paper …

Artificial intelligence in diagnostic pathology

S Shafi, AV Parwani - Diagnostic pathology, 2023 - Springer
Digital pathology (DP) is being increasingly employed in cancer diagnostics, providing
additional tools for faster, higher-quality, accurate diagnosis. The practice of diagnostic …

Time-series representation learning via temporal and contextual contrasting

E Eldele, M Ragab, Z Chen, M Wu, CK Kwoh… - arxiv preprint arxiv …, 2021 - arxiv.org
Learning decent representations from unlabeled time-series data with temporal dynamics is
a very challenging task. In this paper, we propose an unsupervised Time-Series …