Bone, cartilage, and soft tissue regeneration is a complex spatiotemporal process recruiting
a variety of cell types, whose activity and interplay must be precisely mediated for effective …

Inflammatory cardiomyopathy, characterized by inflammatory cell infiltration into the
myocardium and a high risk of deteriorating cardiac function, has a heterogeneous …

Bone has a remarkable endogenous regenerative capacity that enables scarless healing
and restoration of its prior mechanical function, even under challenging conditions such as …

To present knowledge, macrophages are found in all tissues of the human body. They are a
cell population with high plasticity which come with a multitude of functions which appear to …

Age-related T cell dysfunction can lead to failure of immune tolerance mechanisms, resulting
in aberrant T cell-driven cytokine and cytotoxic responses that ultimately cause tissue …

Bioceramics have been extensively used to improve osteogenesis of polymers because of
their excellent bone-forming capabilities. However, the inadequate interfacial bonding …

The regulatory role of the immune system in maintaining bone homeostasis and restoring its
functionality, when disturbed due to trauma or injury, has become evident in recent years …

Zinc (Zn) plays a crucial role in bone metabolism and imbues biodegradable Zn‐based
materials with the ability to promote bone regeneration in bone trauma. However, the impact …

Substantial tissue loss, such as in large bone defects, represents a clinical challenge for
which regenerative therapies and tissue engineering strategies aim at offering treatment …

Multipotent stromal cells are considered attractive sources for cell therapy and tissue
engineering. Despite numerous experimental and clinical studies, broad application of …