miRNAs, a subclass of small regulatory RNAs, are present from ancient unicellular
protozoans to parasitic helminths and parasitic arthropods. The miRNA-silencing …

MicroRNAs (miRNAs) play a variety of roles in diverse biological processes at the post-
transcriptional regulatory level. Although numerous miRNAs have been identified in …

During the chronic stage of Schistosoma infection, the female lays fertile eggs, triggering a
strong anti‐parasitic type 2 helper T‐cell (Th2) immune response. It is unclear how this Th2 …

Insulators help separate active chromatin domains from silenced ones. In yeast, gene
promoters act as insulators to block the spread of Sir and HP1 mediated silencing while in …

The increase of bodyplan complexity in early bilaterian evolution is correlates with the
advent and diversification of microRNAs. These small RNAs guide animal development by …

Background. Schistosomiasis traditionally has been diagnosed by detecting eggs in stool or
urine. However, the sensitivity of these examinations is limited, especially in travelers with a …

The aetiological agent of cystic hydatid disease, the platyhelminth parasite Echinococcus
granulosus, undergoes a series of metamorphic events during its complex life cycle. One of …

The RNA polymerase (Pol) III transcription system is devoted to the production of short,
generally abundant noncoding (nc) RNAs in all eukaryotic cells. Previously thought to be …

Schistosomes, blood flukes, are an important global public health concern. Paired adult
female schistosomes produce large numbers of eggs that are primarily responsible for the …

Background Urogenital schistosomiasis due to Schistosoma haematobium is a serious
underestimated public health problem affecting 112 million people-particularly in sub …