The potential role of ischaemia–reperfusion injury in chronic, relapsing diseases such as rheumatoid arthritis, Long COVID, and ME/CFS: evidence, mechanisms, and …
Ischaemia–reperfusion (I–R) injury, initiated via bursts of reactive oxygen species produced
during the reoxygenation phase following hypoxia, is well known in a variety of acute …
during the reoxygenation phase following hypoxia, is well known in a variety of acute …
Endothelial function assessment by flow-mediated dilation method: a valuable tool in the evaluation of the cardiovascular system
S Mućka, M Miodońska, GK Jakubiak… - International journal of …, 2022 - mdpi.com
Cardiovascular diseases (CVDs) in the course of atherosclerosis are one of the most critical
public health problems in the world. Endothelial cells synthesize numerous biologically …
public health problems in the world. Endothelial cells synthesize numerous biologically …
SGLT2 inhibitor ameliorates endothelial dysfunction associated with the common ALDH2 alcohol flushing variant
The common aldehyde dehydrogenase 2 (ALDH2) alcohol flushing variant known as
ALDH2* 2 affects∼ 8% of the world's population. Even in heterozygous carriers, this …
ALDH2* 2 affects∼ 8% of the world's population. Even in heterozygous carriers, this …
Morphological and functional remodeling of vascular endothelium in cardiovascular diseases
G Bkaily, D Jacques - International Journal of Molecular Sciences, 2023 - mdpi.com
The vascular endothelium plays a vital role during embryogenesis and aging and is a cell
monolayer that lines the blood vessels. The immune system recognizes the endothelium as …
monolayer that lines the blood vessels. The immune system recognizes the endothelium as …
The role of the cell surface glycocalyx in drug delivery to and through the endothelium
Cell membranes are key interfaces where materials engineering meets biology. Traditionally
regarded as just the location of receptors regulating the uptake of molecules, we now know …
regarded as just the location of receptors regulating the uptake of molecules, we now know …
Regeneration and assessment of the endothelial glycocalyx to address cardiovascular disease
Endothelial cell (EC) glycocalyx (GCX) loss permits blood circulating particle infiltration of
the vessel walls and leads to vascular dysfunction, atherosclerosis, and serious downstream …
the vessel walls and leads to vascular dysfunction, atherosclerosis, and serious downstream …
Microvascular leakage as therapeutic target for ischemia and reperfusion injury
JA Kloka, B Friedrichson, P Wülfroth, R Henning… - Cells, 2023 - mdpi.com
Reperfusion injury is a very common complication of various indicated therapies such as the
re-opening of vessels in the myocardium or brain as well as reflow in hemodynamic …
re-opening of vessels in the myocardium or brain as well as reflow in hemodynamic …
Effects of dietary-based weight loss interventions on biomarkers of endothelial function: a systematic review and meta-analysis
Endothelial dysfunction is closely linked to the development of atherosclerosis. This
systematic review and meta-analysis reviewed the evidence on the effect of weight loss …
systematic review and meta-analysis reviewed the evidence on the effect of weight loss …
The effects of folic acid supplementation on endothelial function in adults: a systematic review and dose-response meta-analysis of randomized controlled trials
Background Endothelial dysfunction serves as an early marker for the risk of cardiovascular
disease (CVD); therefore, it is an attractive site of therapeutic interventions to reduce the risk …
disease (CVD); therefore, it is an attractive site of therapeutic interventions to reduce the risk …
Agri-food waste from apple, pear, and sugar beet as a source of protective bioactive molecules for endothelial dysfunction and its major complications
C Caliceti, M Malaguti, L Marracino, MC Barbalace… - Antioxidants, 2022 - mdpi.com
Endothelial damage is recognized as the initial step that precedes several cardiovascular
diseases (CVD), such as atherosclerosis, hypertension, and coronary artery disease. It has …
diseases (CVD), such as atherosclerosis, hypertension, and coronary artery disease. It has …