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Synaptic AMPA receptor composition in development, plasticity and disease
JM Henley, KA Wilkinson - Nature Reviews Neuroscience, 2016 - nature.com
AMPA receptors (AMPARs) are assemblies of four core subunits, GluA1–4, that mediate
most fast excitatory neurotransmission. The component subunits determine the functional …
most fast excitatory neurotransmission. The component subunits determine the functional …
The dynamic synapse
The constant dynamic movement of synapses and their components has emerged in the last
decades as a key feature of synaptic transmission and its plasticity. Intramolecular protein …
decades as a key feature of synaptic transmission and its plasticity. Intramolecular protein …
Super-resolution imaging reveals that AMPA receptors inside synapses are dynamically organized in nanodomains regulated by PSD95
The spatiotemporal organization of neurotransmitter receptors in postsynaptic membranes is
a fundamental determinant of synaptic transmission and information processing by the brain …
a fundamental determinant of synaptic transmission and information processing by the brain …
The role of AMPA receptors in postsynaptic mechanisms of synaptic plasticity
TE Chater, Y Goda - Frontiers in cellular neuroscience, 2014 - frontiersin.org
In the mammalian central nervous system, excitatory glutamatergic synapses harness
neurotransmission that is mediated by ion flow through α-amino-3-hydroxy-5-methyl-4 …
neurotransmission that is mediated by ion flow through α-amino-3-hydroxy-5-methyl-4 …
Balance and stability of synaptic structures during synaptic plasticity
D Meyer, T Bonhoeffer, V Scheuss - Neuron, 2014 - cell.com
Subsynaptic structures such as bouton, active zone, postsynaptic density (PSD) and
dendritic spine, are highly correlated in their dimensions and also correlate with synapse …
dendritic spine, are highly correlated in their dimensions and also correlate with synapse …
Regulation of AMPA receptor trafficking and synaptic plasticity
AMPA receptors (AMPARs) mediate the majority of fast excitatory synaptic transmission in
the brain. Dynamic changes in neuronal synaptic efficacy, termed synaptic plasticity, are …
the brain. Dynamic changes in neuronal synaptic efficacy, termed synaptic plasticity, are …
Molecular mechanisms of early and late LTP
LTP is the most intensively studied cellular model of the memory and generally divided at
least two distinct phases as early and late. E-LTP requires activation of CaMKII that initiates …
least two distinct phases as early and late. E-LTP requires activation of CaMKII that initiates …
Actin in dendritic spines: connecting dynamics to function
Dendritic spines are small actin-rich protrusions from neuronal dendrites that form the
postsynaptic part of most excitatory synapses and are major sites of information processing …
postsynaptic part of most excitatory synapses and are major sites of information processing …
[HTML][HTML] Functional organization of postsynaptic glutamate receptors
N Scheefhals, HD MacGillavry - Molecular and Cellular Neuroscience, 2018 - Elsevier
Glutamate receptors are the most abundant excitatory neurotransmitter receptors in the
brain, responsible for mediating the vast majority of excitatory transmission in neuronal …
brain, responsible for mediating the vast majority of excitatory transmission in neuronal …
Synaptic signaling in learning and memory
MB Kennedy - Cold Spring Harbor perspectives in …, 2016 - cshperspectives.cshlp.org
Learning and memory require the formation of new neural networks in the brain. A key
mechanism underlying this process is synaptic plasticity at excitatory synapses, which …
mechanism underlying this process is synaptic plasticity at excitatory synapses, which …