DNA methylation cancer biomarkers: translation to the clinic

WJ Locke, D Guanzon, C Ma, YJ Liew… - Frontiers in …, 2019 - frontiersin.org
Carcinogenesis is accompanied by widespread DNA methylation changes within the cell.
These changes are characterized by a globally hypomethylated genome with focal …

Guidelines and considerations for the use of system suitability and quality control samples in mass spectrometry assays applied in untargeted clinical metabolomic …

D Broadhurst, R Goodacre, SN Reinke, J Kuligowski… - Metabolomics, 2018 - Springer
Background Quality assurance (QA) and quality control (QC) are two quality management
processes that are integral to the success of metabolomics including their application for the …

Breathing, speaking, coughing or sneezing: What drives transmission of SARS‐CoV‐2?

V Stadnytskyi, P Anfinrud, A Bax - Journal of Internal Medicine, 2021 - Wiley Online Library
The SARS‐CoV‐2 virus is highly contagious, as demonstrated by numerous well‐
documented superspreading events. The infection commonly starts in the upper respiratory …

Collection, particle sizing and detection of airborne viruses

M Pan, JA Lednicky, CY Wu - Journal of applied microbiology, 2019 - academic.oup.com
Viruses that affect humans, animals and plants are often dispersed and transmitted through
airborne routes of infection. Due to current technological deficiencies, accurate …

COVID-19 screening using breath-borne volatile organic compounds

H Chen, X Qi, L Zhang, X Li, J Ma… - Journal of breath …, 2021 - iopscience.iop.org
Rapid screening of COVID-19 is key to controlling the pandemic. However, current nucleic
acid amplification involves lengthy procedures in addition to the discomfort of taking …

Ti3C2Tx MXene-Loaded 3D Substrate toward On-Chip Multi-Gas Sensing with Surface-Enhanced Raman Spectroscopy (SERS) Barcode Readout

K Yang, K Zhu, Y Wang, Z Qian, Y Zhang, Z Yang… - ACS …, 2021 - ACS Publications
Gas sensors lie at the heart of various fields ranging from medical to environmental
sciences, and the demand of gas sensors is instantly expanding. However, in the face of …

Exhaled particles and small airways

B Bake, P Larsson, G Ljungkvist, E Ljungström… - Respiratory …, 2019 - Springer
Background Originally, studies on exhaled droplets explored properties of airborne
transmission of infectious diseases. More recently, the interest focuses on properties of …

Tralokinumab for severe, uncontrolled asthma (STRATOS 1 and STRATOS 2): two randomised, double-blind, placebo-controlled, phase 3 clinical trials

RA Panettieri, U Sjöbring, AM Péterffy… - The Lancet …, 2018 - thelancet.com
Background Tralokinumab is an anti-interleukin-13 human monoclonal antibody developed
for the treatment of severe, uncontrolled asthma. These clinical trials aimed to assess the …

Critical review of volatile organic compound analysis in breath and in vitro cell culture for detection of lung cancer

Z Jia, A Patra, VK Kutty, T Venkatesan - Metabolites, 2019 - mdpi.com
Breath analysis is a promising technique for lung cancer screening. Despite the rapid
development of breathomics in the last four decades, no consistent, robust, and validated …

Electronic nose: A non-invasive technology for breath analysis of diabetes and lung cancer patients

B Behera, R Joshi, GKA Vishnu… - Journal of breath …, 2019 - iopscience.iop.org
In human exhaled breath, more than 3000 volatile organic compounds (VOCs) are found,
which are directly or indirectly related to internal biochemical processes in the body …