The mechanical characterization of cell spheroids, one of the most widely used 3D biology
models in vitro, is a hotspot of current research on the role played by the mechanical …

Durotaxis of cells anchored to the extracellular matrix through focal adhesions has been
systematically studied through both analytical and computational approaches. However …

Size regulation in living organisms is a major unsolved problem in developmental biology.
This is due to the intrinsic complexity of biological growth, which simultaneously involves …

Contractile biopolymer networks, such as the actomyosin meshwork of animal cells, are
ubiquitous in living organisms. The active gel theory, which provides a thermodynamic …

Recent years have witnessed unprecedented growth in interdisciplinary engagement and
collaboration of physical and life sciences, to which the very existence of the Royal Society …

Mechanobiological regulation is a crucial element for tissue development and homeostasis.
Dysregulation of the normal mechanobiological microenvironment of cells is linked to …