[HTML][HTML] Merkel cell carcinoma: epidemiology, prognosis, therapy and unmet medical needs

D Schadendorf, C Lebbé, A Zur Hausen… - European journal of …, 2017 - Elsevier
Merkel cell carcinoma (MCC) is a rare skin cancer that is associated with Merkel cell
polyomavirus infection in most cases. Incidence rates of MCC have increased in past …

The biology and treatment of Merkel cell carcinoma: current understanding and research priorities

PW Harms, KL Harms, PS Moore… - Nature reviews Clinical …, 2018 - nature.com
Merkel cell carcinoma (MCC) is a rare and aggressive skin cancer associated with
advanced age and immunosuppression. Over the past decade, an association has been …

Merkel cell carcinoma: current US incidence and projected increases based on changing demographics

KG Paulson, SY Park, NA Vandeven… - Journal of the American …, 2018 - Elsevier
Background Merkel cell carcinoma (MCC) incidence rates are rising and strongly age-
associated, relevant for an aging population. Objective Determine MCC incidence in the …

Why do viruses cause cancer? Highlights of the first century of human tumour virology

PS Moore, Y Chang - Nature reviews cancer, 2010 - nature.com
The year 2011 marks the centenary of Francis Peyton Rous's landmark experiments on an
avian cancer virus. Since then, seven human viruses have been found to cause 10–15% of …

A cornucopia of human polyomaviruses

JA DeCaprio, RL Garcea - Nature reviews Microbiology, 2013 - nature.com
During the past 6 years, focused virus hunting has led to the discovery of nine new human
polyomaviruses, including Merkel cell polyomavirus, which has been linked to Merkel cell …

Merkel cell polyomavirus and two previously unknown polyomaviruses are chronically shed from human skin

RM Schowalter, DV Pastrana, KA Pumphrey… - Cell host & …, 2010 - cell.com
Mounting evidence indicates that Merkel cell polyomavirus (MCV), a circular double-
stranded DNA virus, is a causal factor underlying a highly lethal form of skin cancer known …

Discovery of a New Human Polyomavirus Associated with Trichodysplasia Spinulosa in an Immunocompromized Patient

E van der Meijden, RWA Janssens, C Lauber… - PLoS …, 2010 - journals.plos.org
The Polyomaviridae constitute a family of small DNA viruses infecting a variety of hosts. In
humans, polyomaviruses can cause infections of the central nervous system, urinary tract …

[HTML][HTML] Human polyomaviruses in disease and cancer

T Dalianis, HH Hirsch - Virology, 2013 - Elsevier
Today the human polyomavirus (HPyV) family consists of 10 members, BK virus (BKV) and
JC virus (JCV) isolated 40 years ago and the more recently identified KI virus (KIPyV), WU …

Merkel cell polyomavirus-infected Merkel cell carcinoma cells require expression of viral T antigens

R Houben, M Shuda, R Weinkam, D Schrama… - Journal of …, 2010 - journals.asm.org
Merkel cell carcinoma (MCC) is the most aggressive skin cancer. Recently, it was
demonstrated that human Merkel cell polyomavirus (MCV) is clonally integrated in∼ 80% of …

Human viruses and cancer

A Morales-Sánchez, EM Fuentes-Pananá - Viruses, 2014 - mdpi.com
The first human tumor virus was discovered in the middle of the last century by Anthony
Epstein, Bert Achong and Yvonne Barr in African pediatric patients with Burkitt's lymphoma …