[HTML][HTML] Anisotropic scaffolds for peripheral nerve and spinal cord regeneration
The treatment of long-gap (> 10 mm) peripheral nerve injury (PNI) and spinal cord injury
(SCI) remains a continuous challenge due to limited native tissue regeneration capabilities …
(SCI) remains a continuous challenge due to limited native tissue regeneration capabilities …
Extracellular vesicles as an emerging frontier in spinal cord injury pathobiology and therapy
Extracellular vesicles (EVs) are membrane-delimited particles that are secreted by nearly all
cell types. EVs mediate crucial physiological functions and pathophysiological processes in …
cell types. EVs mediate crucial physiological functions and pathophysiological processes in …
[HTML][HTML] The role of PI3K/Akt signalling pathway in spinal cord injury
CL **ao, WC Yin, YC Zhong, JQ Luo, LL Liu… - Biomedicine & …, 2022 - Elsevier
Spinal cord injury (SCI) is a severely disabling central nervous system injury with complex
pathological mechanisms that leads to sensory and motor dysfunction. The current treatment …
pathological mechanisms that leads to sensory and motor dysfunction. The current treatment …
Spinal cord repair: from cells and tissue engineering to extracellular vesicles
Spinal cord injury (SCI) is a debilitating condition, often leading to severe motor, sensory, or
autonomic nervous dysfunction. As the holy grail of regenerative medicine, promoting spinal …
autonomic nervous dysfunction. As the holy grail of regenerative medicine, promoting spinal …
Spinal cord injury-induced cognitive impairment: A narrative review
OV Alcántar-Garibay… - Neural Regeneration …, 2022 - journals.lww.com
Spinal cord injury is a serious damage to the spinal cord that can lead to life-long disability.
Based on its etiology, spinal cord injury can be classified as traumatic or non-traumatic …
Based on its etiology, spinal cord injury can be classified as traumatic or non-traumatic …
Strategies and prospects of effective neural circuits reconstruction after spinal cord injury
B Yang, F Zhang, F Cheng, L Ying, C Wang, K Shi… - Cell Death & …, 2020 - nature.com
Due to the disconnection of surviving neural elements after spinal cord injury (SCI), such
patients had to suffer irreversible loss of motor or sensory function, and thereafter enormous …
patients had to suffer irreversible loss of motor or sensory function, and thereafter enormous …
Mesenchymal stem cell-derived exosomes containing miR-145-5p reduce inflammation in spinal cord injury by regulating the TLR4/NF-κB signaling pathway
Z Jiang, J Zhang - Cell Cycle, 2021 - Taylor & Francis
EXs (Exosomes) secreted by mesenchymal stem cells (MSCs) have the potential to treat
spinal cord injury (SCI), this study aimed to further explore the therapeutic effect of EXs on …
spinal cord injury (SCI), this study aimed to further explore the therapeutic effect of EXs on …
Progranulin deficiency exacerbates spinal cord injury by promoting neuroinflammation and cell apoptosis in mice
C Wang, L Zhang, JDLC Ndong… - Journal of …, 2019 - Springer
Purpose Spinal cord injury (SCI) often results in significant and catastrophic dysfunction and
disability and imposes a huge economic burden on society. This study aimed to determine …
disability and imposes a huge economic burden on society. This study aimed to determine …
The roles and applications of neural stem cells in spinal cord injury repair
W Guo, X Zhang, J Zhai, J Xue - Frontiers in Bioengineering and …, 2022 - frontiersin.org
Spinal cord injury (SCI), which has no current cure, places a severe burden on patients.
Stem cell-based therapies are considered promising in attempts to repair injured spinal …
Stem cell-based therapies are considered promising in attempts to repair injured spinal …
[HTML][HTML] Advanced approaches to regenerate spinal cord injury: the development of cell and tissue engineering therapy and combinational treatments
Spinal cord injury (SCI) is a central nervous system (CNS) devastate event that is commonly
caused by traumatic or non-traumatic events. The reinnervation of spinal cord axons is …
caused by traumatic or non-traumatic events. The reinnervation of spinal cord axons is …