Redox homeostasis is a delicate balancing act of maintaining appropriate levels of
antioxidant defense mechanisms and reactive oxidizing oxygen and nitrogen species. Any …

Collagen crosslinking provides the mechanical strength required for physiological
maintenance of the extracellular matrix in most tissues in the human body, including the …

Each day, about 2000 US workers have a job-related eye injury requiring medical treatment.
Corneal diseases are the fifth cause of blindness worldwide. Most of these diseases can be …

Keratoconus (KC) is a common corneal ectatic disease that affects 1: 500–1: 2000 people
worldwide and is associated with a progressive thinning of the corneal stroma that may lead …

Abstract Keratoconus (KC) affects 1: 2000 people and is a disorder where cornea thins and
assumes a conical shape. Advanced KC requires surgery to maintain vision. The role of …

Recapitulation of human corneal stromal tissue is believed to be among the most
challenging steps in engineering human corneal tissue because of the difficulty in …

Hormones play a critical role in regulating tissue function by promoting cell survival,
proliferation and differentiation. Our study explores the influence of endocrine function in …

Introduction Keratoconus (KC) is a complex, genetically heterogeneous multifactorial
degenerative disorder characterized by corneal ectasia and thinning. Its incidence is …

Corneal fibrosis (or scarring) occurs in response to ocular trauma or infection, and by
reducing corneal transparency, it can lead to visual impairment and blindness. Studies …

Background Keratoconus (KC) is a common multifactorial ectatic corneal disease with
unknown onset. KC most commonly appears in adolescence and affects approximately 1 …