Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering

MP Lutolf, JA Hubbell - Nature biotechnology, 2005 - nature.com
New generations of synthetic biomaterials are being developed at a rapid pace for use as
three-dimensional extracellular microenvironments to mimic the regulatory characteristics of …

Mechanisms of mesenchymal stem/stromal cell function

JL Spees, RH Lee, CA Gregory - Stem cell research & therapy, 2016 - Springer
The past decade has seen an explosion of research directed toward better understanding of
the mechanisms of mesenchymal stem/stromal cell (MSC) function during rescue and repair …

Geometric cues for directing the differentiation of mesenchymal stem cells

KA Kilian, B Bugarija, BT Lahn, M Mrksich - Proceedings of the National …, 2010 - pnas.org
Significant efforts have been directed to understanding the factors that influence the lineage
commitment of stem cells. This paper demonstrates that cell shape, independent of soluble …

Biomaterials for articular cartilage tissue engineering: Learning from biology

AR Armiento, MJ Stoddart, M Alini, D Eglin - Acta biomaterialia, 2018 - Elsevier
Articular cartilage is commonly described as a tissue that is made of up to 80% water, is
devoid of blood vessels, nerves, and lymphatics, and is populated by only one cell type, the …

Mesenchymal stem/stromal cell-based therapy: mechanism, systemic safety and biodistribution for precision clinical applications

WZ Zhuang, YH Lin, LJ Su, MS Wu, HY Jeng… - Journal of biomedical …, 2021 - Springer
Mesenchymal stem/stromal cells (MSCs) are a promising resource for cell-based therapy
because of their high immunomodulation ability, tropism towards inflamed and injured …

[HTML][HTML] Mechanisms involved in the therapeutic properties of mesenchymal stem cells

L da Silva Meirelles, AM Fontes, DT Covas… - Cytokine & growth factor …, 2009 - Elsevier
Mesenchymal stem cells (MSCs) have been described as being able to give rise to several
quite different mesenchymal cell phenotypes. However, the ability to differentiate is not the …

Immunomodulatory properties of mesenchymal stromal cells

AJ Nauta, WE Fibbe - Blood, The Journal of the American …, 2007 - ashpublications.org
Mesenchymal stem cells (MSCs) are multipotential nonhematopoietic progenitor cells
capable of differentiating into multiple lineages of the mesenchyme. MSCs have emerged as …

Mesenchymal stem cells: environmentally responsive therapeutics for regenerative medicine

MB Murphy, K Moncivais, AI Caplan - Experimental & molecular …, 2013 - nature.com
Mesenchymal stem cells (MSCs) are partially defined by their ability to differentiate into
tissues including bone, cartilage and adipose in vitro, but it is their trophic, paracrine and …

Tendon injury and tendinopathy: healing and repair

P Sharma, N Maffulli - JBJS, 2005 - journals.lww.com
JBJS JBJS Journal Case Connector Reviews JBJS.org Surgical Techniques Open Access
JOPA Log in Subscribe to journalSubscribe Get new issue alertsGet alerts Secondary Logo …

The role of reactive oxygen species in mesenchymal stem cell adipogenic and osteogenic differentiation: a review

F Atashi, A Modarressi, MS Pepper - Stem cells and development, 2015 - liebertpub.com
Mesenchymal stromal cells (MSCs) are promising candidates for tissue engineering and
regenerative medicine. The multipotent stem cell component of MSC isolates is able to …