Due to the restricted intrinsic capacity of resident chondrocytes to regenerate the lost
cartilage postinjury, stem cell‐based therapies have been proposed as a novel therapeutic …

Skeleton has emerged as an endocrine organ which is both capable of regulating energy
metabolism and being a target for it. Glutamine is the most bountiful and flexible amino acid …

Abstract Background/Aims One of the main concerns for maxillofacial and orthopedic
surgeons is finding a method to improve regeneration of large craniofacial bone defects. The …

Osteoarthritis (OA) is a prevalent chronic disease impacting on quality of life and has
societal and economical burden increasing with age. Yet, no confirmed pharmacological …

Adipose-derived mesenchymal stem cell (ADSC) with a high capacity of chondrogenic
differentiation was a promising candidate for cartilage defect treatment. This study's …

Articular cartilage defect remains the most challenging joint disease due to limited intrinsic
healing capacity of the cartilage that most often progresses to osteoarthritis. In recent years …

Objective: In recent times, it has been recognized that mesenchymal stem cells (MSCs)
possess the capability to address osteoarthritis (OA). The objective of this research was to …

Objective: The aim of this study was to evaluate the effectiveness of the application of
cultured autologous bone marrow mesenchymal stem cells (BMSCs) with scaffold and low …

BACKGROUND Restoration of craniofacial bone defects has been a concern for oral and
maxillofacial surgeons. In this study, the healing effect of fibrin glue scaffold was compared …

Repairing osteochondral defects to restore joint function is a major challenge in
regenerative medicine. However, with recent advances in tissue engineering, the …