Many multicellular systems problems can only be understood by studying how cells move,
grow, divide, interact, and die. Tissue-scale dynamics emerge from systems of many …

Oxygen deprivation can be detrimental. However, chronic hypoxia is also associated with
decreased incidence of metabolic syndrome and cardiovascular disease in high-altitude …

Non-coding RNAs (ncRNAs) are a heterogeneous group, in terms of structure and sequence
length, consisting of RNA molecules that do not code for proteins. These ncRNAs have a …

Background: Chemoresistance is a vital problem in cancer therapy where cancer cells
develop mechanisms to encounter the effect of chemotherapeutics, resulting in cancer …

Background Pancreatic cancer is a complex disease with a desmoplastic stroma, extreme
hypoxia, and inherent resistance to therapy. Understanding the signaling and adaptive …

Background: Hypoxic condition induces molecular alterations which affect the survival rate
and chemo-resistant phenotype of cancer cells. Objective: The aim of this study is to …

Real-time surveillance of photodynamic therapy (PDT) has been desired by the research
community for a long time. The impact of the treatment is encoded in the phosphorescence …

Hypoxia is an environmental cue that is associated with multiple tumorigenic processes
such as immunosuppression, angiogenesis, cancer invasion, metastasis, drug resistance …

Kaposi's sarcoma associated herpesvirus (KSHV), like all herpesviruses maintains lifelong
persistence with its host genome in latently infected cells with only a small fraction of cells …

Multiple myeloma (MM) is the second most common hematologic malignancy, which is
characterized by clonal proliferation of neoplastic plasma cells in the bone marrow. This …