Prefrontal cortex development in health and disease: lessons from rodents and humans

M Chini, IL Hanganu-Opatz - Trends in neurosciences, 2021 - cell.com
The role of the prefrontal cortex (PFC) takes center stage among unanswered questions in
modern neuroscience. The PFC has a Janus-faced nature: it enables sophisticated cognitive …

How development sculpts hippocampal circuits and function

R Cossart, R Khazipov - Physiological Reviews, 2022 - journals.physiology.org
In mammals, the selective transformation of transient experience into stored memory occurs
in the hippocampus, which develops representations of specific events in the context in …

Resolving the prefrontal mechanisms of adaptive cognitive behaviors: A cross-species perspective

IL Hanganu-Opatz, T Klausberger, T Sigurdsson… - Neuron, 2023 - cell.com
The prefrontal cortex (PFC) enables a staggering variety of complex behaviors, such as
planning actions, solving problems, and adapting to new situations according to external …

Loss of spines in the prelimbic cortex is detrimental to working memory in mice with early-life adversity

L Xu, Y Liu, J Long, X He, F ** neocortical circuits in health and disease
IL Hanganu-Opatz, SJB Butt… - Journal of …, 2021 - Soc Neuroscience
The sensory and cognitive abilities of the mammalian neocortex are underpinned by
intricate columnar and laminar circuits formed from an array of diverse neuronal populations …

The role of aberrant neural oscillations in the hippocampal-medial prefrontal cortex circuit in neurodevelopmental and neurological disorders

N Shing, MC Walker, P Chang - Neurobiology of Learning and Memory, 2022 - Elsevier
The hippocampus (HPC) and medial prefrontal cortex (mPFC) have well-established roles in
cognition, emotion, and sensory processing. In recent years, interests have shifted towards …