The tumor microenvironment (TME) play critical roles in tumor survival, progression, and
metastasis and can be considered potential targets for molecular imaging of cancer. The …

Ultrasound (US) imaging, due to its capabilities of real-time imaging, portability, low cost and
favorable safety, is frequently used as a diagnostic modality for the visualization of different …

Gas-filled microbubbles are currently in clinical use as blood pool contrast agents for
ultrasound imaging. The goal of this review is to discuss the trends and issues related to …

Fibroblasts are highly heterogeneous mesenchymal stromal cells, and different fibroblast
subpopulations play different roles. A subpopulation of fibroblasts expressing CD90, a 25 …

Early detection is crucial for improving survival rates of pancreatic ductal adenocarcinoma
(PDA), yet current diagnostic methods can often fail at this stage. Recently, there has been …

The main aim of this study is to synthesize contrast microbubbles (MB) functionalized with
engineered protein ligands using a microfluidic device to target breast cancer specific …

Pancreatic ductal adenocarcinoma (PDAC) is often associated with a poor prognosis due to
silent onset, resistance to therapies, and rapid spreading. Most patients are ineligible for …

Therapeutic microbubbles (thMBs) contain drug-filled liposomes linked to microbubbles and
targeted to vascular proteins. Upon the application of a destructive ultrasound trigger, drug …

Molecular imaging using singlechain variable fragments (scFv) of antibodies targeting
cancer specific antigens have been considered a non-immunogenic approach for early …

Objectives Ultrasound contrast agents, consisting of gas-filled microbubbles (MBs), have
been imaged using several techniques that include ultrasound localization microscopy and …