Cerebrospinal fluid (CSF) plays a critical role in metabolic waste clearance from the brain,
requiring its circulation throughout various brain pathways, including the ventricular system …

The discovery of the glymphatic system has revolutionized our understanding of
cerebrospinal fluid (CSF) circulation and interstitial waste clearance in the brain. This …

The glymphatic system and the meningeal lymphatic vessels provide a pathway for transport
of solutes and clearance of toxic material from the brain. Of specific relevance to ALS, this is …

The ALPS-index was found to be an indicator of a number of conditions related to the
glymphatic system. Thus, although this was expected in the original report, the results of the …

Abstract Purpose of Review The glymphatic system is hypothesized to act as the brain's
filtration system to remove toxic solutes that accumulate throughout the day. Perivascular …

Background Traumatic brain injury (TBI) is a major cause of morbidity and mortality, affecting
millions annually worldwide. Although the majority of TBI patients return to premorbid …

Purpose of review We aim to critically review animal and human studies of the glymphatic
system in migraine and propose a model for how the glymphatic system may function in …

Traumatic brain injury (TBI) is a common cause of neurologic morbidity for which few
effective therapies exist, especially during the chronic stage. A potential therapy for chronic …

Background Perivascular spaces (PVS) visible on magnetic resonance imaging (MRI) are
significant markers associated with various neurological diseases. Although quantitative …

BACKGROUND: Recent studies, using diffusion tensor image analysis along the
perivascular space (DTI-ALPS), suggest impaired perivascular space (PVS) function in …