The placenta is essential for the efficient delivery of nutrients and oxygen from mother to
fetus to maintain normal fetal growth. Dysfunctional placental development underpins many …

Abstract Over 30 years ago Professor David Barker first proposed the theory that events in
early life could explain an individual's risk of non‐communicable disease in later life: the …

Fetal growth restriction (FGR) affects 5–10% of pregnancies, leading to clinically significant
fetal morbidity and mortality. FGR placentae frequently exhibit poor vascular branching, but …

The placenta provides the vital nutrients and removal of waste products required for fetal
growth and development. Understanding and quantifying the differences in structure and …

The placenta mediates physiological exchange between the mother and the fetus. In
placental mammals, all placentas are descended from a single common ancestor and …

Experimental methods that allow examination of the intact vascular network of large organs,
such as the human placenta are limited, preventing adequate comparison of normal and …

Purpose Placental function is key for successful human pregnancies. Perfusion may be a
sensitive marker for the in vivo assessment of placental function. Arterial spin labeling (ASL) …

The ability of the baby to receive nutrients and oxygen in utero depends on the healthy
development of the placenta. For maternal blood to adequately perfuse the placenta, it …

The utero-placental circulation links the maternal and fetal circulations during pregnancy,
ensuring adequate gas and nutrient exchange, and consequently fetal growth. However, our …

The placenta is a multifunctional organ that exchanges blood gases and nutrients between a
mother and her develo** fetus. In humans, fetal blood flows through intricate networks of …