Living leukocyte‐based drug delivery systems

Y Chen, D Qin, J Zou, X Li, XD Guo, Y Tang… - Advanced …, 2023 - Wiley Online Library
Leukocytes play a vital role in immune responses, including defending against invasive
pathogens, reconstructing impaired tissue, and maintaining immune homeostasis. When the …

Anti-inflammatory effects of resveratrol: Mechanistic insights

D de Sá Coutinho, MT Pacheco, RL Frozza… - International journal of …, 2018 - mdpi.com
Inflammation is the principal response invoked by the body to address injuries. Despite
inflammation constituting a crucial component of tissue repair, it is well known that …

Anti-inflammatory activity of natural stilbenoids: A review

M Dvorakova, P Landa - Pharmacological Research, 2017 - Elsevier
Resveratrol and other natural stilbenoids, including piceatannol, pterostilbene, and gnetol,
are well-known anti-inflammatory compounds with indisputable activity in vitro as well as in …

Nanomaterials-based electrochemical sensors and biosensors for the detection of non-steroidal anti-inflammatory drugs

PK Kalambate, J Noiphung, N Rodthongkum… - TrAC Trends in …, 2021 - Elsevier
Non-steroidal anti-inflammatory drugs (NSAIDs) are the most frequently administered over-
the-counter medicines to treat fever, pain and control inflammation. However, their overdose …

NSAID induced gastrointestinal damage and designing GI-sparing NSAIDs

G García-Rayado, M Navarro… - Expert review of clinical …, 2018 - Taylor & Francis
NSAIDs are widely used to treat pain and rheumatic conditions, but they induce adverse
events in different body systems, although the major, most frequent events occur in the …

Bioresponsive nanoparticles targeted to infectious microenvironments for sepsis management

CY Zhang, J Gao, Z Wang - Advanced materials, 2018 - Wiley Online Library
Sepsis is a life‐threatening disease resulted from a dysregulated host immune response to
bacterial infections, continuing to cause high morbidity and mortality worldwide. Despite …

Neutrophils enable local and non‐invasive liposome delivery to inflamed skeletal muscle and ischemic heart

J Che, A Najer, AK Blakney, PF McKay… - Advanced …, 2020 - Wiley Online Library
Uncontrolled inflammation is a major pathological factor underlying a range of diseases
including autoimmune conditions, cardiovascular disease, and cancer. Improving localized …

Macrophage-targeted hydroxychloroquine nanotherapeutics for rheumatoid arthritis therapy

H Fang, Y Sha, L Yang, J Jiang, L Yin, J Li… - … applied materials & …, 2022 - ACS Publications
Rheumatoid arthritis (RA) is an autoimmune disease with unclear pathogenesis.
Hydroxychloroquine (HCQ), despite its moderate anti-RA efficacy, is among the few clinical …

Role of inflammatory mediators, macrophages, and neutrophils in glioma maintenance and progression: mechanistic understanding and potential therapeutic …

AS Basheer, F Abas, I Othman, R Naidu - Cancers, 2021 - mdpi.com
Simple Summary The tumor microenvironment is a complex network comprised of
neoplastic and a variety of immune cells, proteins, and inflammatory mediators. Previous …

Inflammation-targeting polymeric nanoparticles deliver sparfloxacin and tacrolimus for combating acute lung sepsis

Y Yang, Y Ding, B Fan, Y Wang, Z Mao, W Wang… - Journal of Controlled …, 2020 - Elsevier
Sepsis is a complex disorder with very high morbidity and mortality; it can occur when an
immune disorder triggers an invasion of pathogens in the host. Although many potential anti …