The onset of heart failure is typically preceded by cardiac hypertrophy, a response of the
heart to increased workload, a cardiac insult such as a heart attack or genetic mutation …

MicroRNAs (miRNAs) are small, non-coding, RNA molecules approximately 22 nucleotides
in length which act as post-transcriptional regulators of gene expression. Individual miRNAs …

Background—Small RNA molecules, called microRNAs, freely circulate in human plasma
and correlate with varying pathologies. In this study, we explored their diagnostic potential in …

Noncoding RNA s are emerging as potent and multifunctional regulators in all biological
processes. In parallel, a rapidly growing number of studies has unravelled associations …

Research showing that microRNAs (miRNAs) are versatile regulators of gene expression
has instigated tremendous interest in cardiovascular research. The overwhelming majority of …

Pathological growth of cardiomyocytes (hypertrophy) is a major determinant for the
development of heart failure, one of the leading medical causes of mortality worldwide. Here …

Cardiovascular disease is the predominant cause of human morbidity and mortality in
developed countries. Thus, extraordinary effort has been devoted to determining the …

MicroRNAs (miRNAs) are increasingly recognized to play important roles in cardiovascular
diseases, including heart failure. These small, non‐coding RNAs have been identified in …

Abstract Cardiac miRNAs (miR-1, miR133a, miR-208a/b, and miR-499) are abundantly
expressed in the myocardium. They play a central role in cardiogenesis, heart function and …

Adult humans fail to regenerate their hearts following injury, and this failure to regenerate
myocardium is a leading cause of heart failure and death worldwide. Although all adult …