Many features of cell behavior are regulated by Rho family GTPases, but the most profound
effects of these proteins are on the actin cytoskeleton and it was these that first drew …

The Rho-family proteins make up a major branch of the Ras superfamily of small GTPases.
To date, 22 human genes encoding at least 25 proteins have been described. The best …

Cytochrome P450 proteins (CYP450s) are membrane-associated haem proteins that
metabolize physiologically important compounds in many species of microorganisms, plants …

Phosphatidylserine recognition receptors are a highly diverse set of receptors grouped by
their ability to recognize the 'eat‐me'signal phosphatidylserine on apoptotic cells. Most of the …

Many fundamental processes in cell biology are regulated by Rho GTPases, including cell
adhesion, migration and differentiation. While regulating cellular functions, members of the …

W ing and becoming stronger over time. Rac and Cdc42, the Rho-like small GTPases, were
activated when E-cadherin–expressing cells formed aggregates in suspension …

Eph receptors transduce short-range repulsive signals for axon guidance by modulating
actin dynamics within growth cones. We report the cloning and characterization of ephexin …

Microtubules are involved in actin-based protrusion at the leading-edge lamellipodia of
migrating fibroblasts. Here we show that the growth of microtubules induced in fibroblasts by …

The Rho GTPases are related to the Ras proto-oncogenes and consist of 22 family
members. These proteins have important roles in regulating the organization of the actin …

Two different condensin complexes make distinct contributions to metaphase chromosome
architecture in vertebrate cells. We show here that the spatial and temporal distributions of …