Bioadhesive technology platforms

SJ Wu, X Zhao - Chemical Reviews, 2023‏ - ACS Publications
Bioadhesives have emerged as transformative and versatile tools in healthcare, offering the
ability to attach tissues with ease and minimal damage. These materials present numerous …

[HTML][HTML] A comprehensive review on various techniques used for synthesizing nanoparticles

S Kumari, S Raturi, S Kulshrestha, K Chauhan… - Journal of Materials …, 2023‏ - Elsevier
Nature is still the main focus of scientific and technological research, particularly in
nanotechnology and because of its remarkable properties; nanotechnology has acquired …

Engineering the next generation of cell-based therapeutics

CJ Bashor, IB Hilton, H Bandukwala… - Nature Reviews Drug …, 2022‏ - nature.com
Cell-based therapeutics are an emerging modality with the potential to treat many currently
intractable diseases through uniquely powerful modes of action. Despite notable recent …

Developments in stem cell-derived islet replacement therapy for treating type 1 diabetes

NJ Hogrebe, M Ishahak, JR Millman - Cell Stem Cell, 2023‏ - cell.com
The generation of islet-like endocrine clusters from human pluripotent stem cells (hPSCs)
has the potential to provide an unlimited source of insulin-producing β cells for the treatment …

Soft materials by design: unconventional polymer networks give extreme properties

X Zhao, X Chen, H Yuk, S Lin, X Liu… - Chemical Reviews, 2021‏ - ACS Publications
Hydrogels are polymer networks infiltrated with water. Many biological hydrogels in animal
bodies such as muscles, heart valves, cartilages, and tendons possess extreme mechanical …

Bioactive materials promote wound healing through modulation of cell behaviors

R Li, K Liu, X Huang, D Li, J Ding, B Liu… - Advanced …, 2022‏ - Wiley Online Library
Skin wound repair is a multistage process involving multiple cellular and molecular
interactions, which modulate the cell behaviors and dynamic remodeling of extracellular …

[HTML][HTML] Solid implantable devices for sustained drug delivery

E Magill, S Demartis, E Gavini, AD Permana… - Advanced Drug Delivery …, 2023‏ - Elsevier
Implantable drug delivery systems (IDDS) are an attractive alternative to conventional drug
administration routes. Oral and injectable drug administration are the most common routes …

Engineering living therapeutics with synthetic biology

A Cubillos-Ruiz, T Guo, A Sokolovska… - Nature Reviews Drug …, 2021‏ - nature.com
The steadfast advance of the synthetic biology field has enabled scientists to use genetically
engineered cells, instead of small molecules or biologics, as the basis for the development …

Foreign body reaction to implanted biomaterials and its impact in nerve neuroprosthetics

A Carnicer-Lombarte, ST Chen… - … in Bioengineering and …, 2021‏ - frontiersin.org
The implantation of any foreign material into the body leads to the development of an
inflammatory and fibrotic process—the foreign body reaction (FBR). Upon implantation into a …

Immunomodulatory biomaterials for tissue repair

R Whitaker, B Hernaez-Estrada, RM Hernandez… - Chemical …, 2021‏ - ACS Publications
All implanted biomaterials are targets of the host's immune system. While the host
inflammatory response was once considered a detrimental force to be blunted or avoided, in …