DNA walkers for biosensing development

L Song, Y Zhuge, X Zuo, M Li, F Wang - Advanced Science, 2022 - Wiley Online Library
The ability to design nanostructures with arbitrary shapes and controllable motions has
made DNA nanomaterials used widely to construct diverse nanomachines with various …

[HTML][HTML] Nucleic acid nanoassembly-enhanced RNA therapeutics and diagnosis

M Zhao, R Wang, K Yang, Y Jiang, Y Peng, Y Li… - … Pharmaceutica Sinica B, 2023 - Elsevier
RNAs are involved in the crucial processes of disease progression and have emerged as
powerful therapeutic targets and diagnostic biomarkers. However, efficient delivery of …

Isothermal amplification for microRNA detection: from the test tube to the cell

R Deng, K Zhang, J Li - Accounts of chemical research, 2017 - ACS Publications
Conspectus MicroRNAs (miRNAs) are a class of small noncoding RNAs that act as pivotal
post-transcriptional regulators of gene expression, thus involving in many fundamental …

High-Fidelity and Rapid Quantification of miRNA Combining crRNA Programmability and CRISPR/Cas13a trans-Cleavage Activity

Y Shan, X Zhou, R Huang, D **ng - Analytical chemistry, 2019 - ACS Publications
MicroRNAs (miRNAs) are short noncoding RNAs that post-transcriptionally regulate gene
expression. It has been proved that the aberrant expression of miRNAs is related to disease …

An enzyme-free molecular catalytic device: dynamically self-assembled DNA dendrimers for in situ imaging of microRNAs in live cells

S Yue, X Song, W Song, S Bi - Chemical Science, 2019 - pubs.rsc.org
DNA has become a promising material to construct high-order structures and molecular
devices owing to its sequence programmability. Herein, a DNA machine based on branched …

Recent progresses in DNA nanostructure-based biosensors for detection of tumor markers

R Huang, N He, Z Li - Biosensors and Bioelectronics, 2018 - Elsevier
DNA has emerged as a promising biomaterial for assembling a variety of nanostructures
based on its programmable base pairing. It also has other remarkable properties including …

Recent advances in microRNA detection

Y Cheng, L Dong, J Zhang, Y Zhao, Z Li - Analyst, 2018 - pubs.rsc.org
The development of simple, robust, and reliable microRNA (miRNA) detection methods is of
great significance in the studies of the biological function of miRNAs, molecular diagnostics …

A bipedal DNA nanowalker fueled by catalytic assembly for imaging of base-excision repairing in living cells

MM Lv, JW Liu, RQ Yu, JH Jiang - Chemical science, 2020 - pubs.rsc.org
DNA nanowalkers moving progressively along a prescribed DNA track are useful tools in
biosensing, molecular theranostics and biosynthesis. However, stochastic DNA …

Smart DNA machine for carcinoembryonic antigen detection by exonuclease III-assisted target recycling and DNA walker cascade amplification

MQ He, K Wang, WJ Wang, YL Yu… - Analytical …, 2017 - ACS Publications
A synthetic DNA machine performs quasi-mechanical movements in response to external
intervention, suggesting the promise of constructing sensitive and specific biosensors …

Two-color imaging of microRNA with enzyme-free signal amplification via hybridization chain reactions in living cells

L Li, J Feng, H Liu, Q Li, L Tong, B Tang - Chemical Science, 2016 - pubs.rsc.org
In situ imaging of miRNA in living cells could facilitate the monitoring of the dynamic
expression and distribution of miRNA and research on miRNA-related cellular processes …